Background The literature regarding clinical olfaction, olfactory loss, and olfactory
dysfunction has expanded rapidly over the past two decades, with an exponential rise in the …

Generation of neuronal diversity is a biological strategy widely used in the brain to process
complex information. The olfactory bulb is the first relay station of olfactory information in the …

The central processing pathways of the human olfactory system are not fully understood.
The olfactory bulb projects directly to a number of cortical brain structures, but the distinct …

Olfactory deficits are present in numerous neurodegenerative disorders and are
accompanied by pathology in related brain regions. In several of these disorders, olfactory …

Elucidating the neural circuits supporting odor identification remains an open challenge.
Here, we analyze the contribution of the two output cell types of the mouse olfactory bulb …

The mediodorsal thalamic nucleus (MDT) is a higher order thalamic nucleus and its role in
cognition is increasingly well established. Interestingly, components of the MDT also have a …

Functional magnetic imaging (fMRI) has been widely used to examine the functional neural
networks in both the evoked and resting states. However, most fMRI studies in rodents are …

Pleasant odorants are represented in the posterior olfactory bulb (pOB) in mice. How does
this hedonic information generate odor-motivated behaviors? Using optogenetics, we report …

Rodents can successfully learn multiple novel stimulus–response associations after only a
few repetitions when the contingencies predict reward. The circuits modified during such …

Odor-preferences are usually influenced by life experiences. However, the neural circuit
mechanisms remain unclear. The medial olfactory tubercle (mOT) is involved in both reward …