[HTML][HTML] Advances in hydrogel-based vascularized tissues for tissue repair and drug screening
The construction of biomimetic vasculatures within the artificial tissue models or organs is
highly required for conveying nutrients, oxygen, and waste products, for improving the …
highly required for conveying nutrients, oxygen, and waste products, for improving the …
[HTML][HTML] Organ-on-a-chip meets artificial intelligence in drug evaluation
S Deng, C Li, J Cao, Z Cui, J Du, Z Fu, H Yang… - Theranostics, 2023 - ncbi.nlm.nih.gov
Drug evaluation has always been an important area of research in the pharmaceutical
industry. However, animal welfare protection and other shortcomings of traditional drug …
industry. However, animal welfare protection and other shortcomings of traditional drug …
Microfluidic organ-on-a-chip system for disease modeling and drug development
Z Li, J Hui, P Yang, H Mao - Biosensors, 2022 - mdpi.com
An organ-on-a-chip is a device that combines micro-manufacturing and tissue engineering
to replicate the critical physiological environment and functions of the human organs …
to replicate the critical physiological environment and functions of the human organs …
3D Biomimetic Models to Reconstitute Tumor Microenvironment In Vitro: Spheroids, Organoids, and Tumor‐on‐a‐Chip
W Li, Z Zhou, X Zhou, BL Khoo… - Advanced …, 2023 - Wiley Online Library
Decades of efforts in engineering in vitro cancer models have advanced drug discovery and
the insight into cancer biology. However, the establishment of preclinical models that enable …
the insight into cancer biology. However, the establishment of preclinical models that enable …
Recent advances for cancer detection and treatment by microfluidic technology, review and update
N Bargahi, S Ghasemali, S Jahandar-Lashaki… - Biological Procedures …, 2022 - Springer
Numerous cancer-associated deaths are owing to a lack of effective diagnostic and
therapeutic approaches. Microfluidic systems for analyzing a low volume of samples offer a …
therapeutic approaches. Microfluidic systems for analyzing a low volume of samples offer a …
Advanced microfluidic technologies for lipid nano-microsystems from synthesis to biological application
Microfluidics is an emerging technology that can be employed as a powerful tool for
designing lipid nano-microsized structures for biological applications. Those lipid structures …
designing lipid nano-microsized structures for biological applications. Those lipid structures …
Organ-on-a-chip platforms for drug screening and delivery in tumor cells: A systematic review
IM Gonçalves, V Carvalho, RO Rodrigues, D Pinho… - Cancers, 2022 - mdpi.com
Simple Summary Cancer is one of the diseases with a high mortality rate worldwide. Of the
current strategies to study new diagnostic and treating tools, organs-on-chip are quite …
current strategies to study new diagnostic and treating tools, organs-on-chip are quite …
Design and engineering of organ-on-a-chip
S Cho, S Lee, SI Ahn - Biomedical engineering letters, 2023 - Springer
Abstract Organ-on-a-chip (OOC) is an emerging interdisciplinary technology that
reconstitutes the structure, function, and physiology of human tissues as an alternative to …
reconstitutes the structure, function, and physiology of human tissues as an alternative to …
Angiogenesis-on-a-chip coupled with single-cell RNA sequencing reveals spatially differential activations of autophagy along angiogenic sprouts
Several functions of autophagy associated with proliferation, differentiation, and migration of
endothelial cells have been reported. Due to lack of models recapitulating angiogenic …
endothelial cells have been reported. Due to lack of models recapitulating angiogenic …
Microfluidics in vascular biology research: a critical review for engineers, biologists, and clinicians
G Simitian, M Virumbrales-Muñoz… - Lab on a Chip, 2022 - pubs.rsc.org
Neovascularization, the formation of new blood vessels, has received much research
attention due to its implications for physiological processes and diseases. Most studies …
attention due to its implications for physiological processes and diseases. Most studies …