Horizontal gene transfer among host-associated microbes
Horizontal gene transfer is an important evolutionary force, facilitating bacterial diversity. It is
thought to be pervasive in host-associated microbiomes, where bacterial densities are high …
thought to be pervasive in host-associated microbiomes, where bacterial densities are high …
Selfish, promiscuous and sometimes useful: how mobile genetic elements drive horizontal gene transfer in microbial populations
M Haudiquet, JM de Sousa… - … Transactions of the …, 2022 - royalsocietypublishing.org
Horizontal gene transfer (HGT) drives microbial adaptation but is often under the control of
mobile genetic elements (MGEs) whose interests are not necessarily aligned with those of …
mobile genetic elements (MGEs) whose interests are not necessarily aligned with those of …
Bacteriophages benefit from mobilizing pathogenicity islands encoding immune systems against competitors
Bacteria encode sophisticated anti-phage systems that are diverse and versatile and display
high genetic mobility. How this variability and mobility occurs remains largely unknown …
high genetic mobility. How this variability and mobility occurs remains largely unknown …
Bacterial chromosomal mobility via lateral transduction exceeds that of classical mobile genetic elements
S Humphrey, A Fillol-Salom, N Quiles-Puchalt… - Nature …, 2021 - nature.com
It is commonly assumed that the horizontal transfer of most bacterial chromosomal genes is
limited, in contrast to the frequent transfer observed for typical mobile genetic elements …
limited, in contrast to the frequent transfer observed for typical mobile genetic elements …
Identification and characterization of thousands of bacteriophage satellites across bacteria
JAM de Sousa, A Fillol-Salom, JR Penadés… - Nucleic acids …, 2023 - academic.oup.com
Bacteriophage–bacteria interactions are affected by phage satellites, elements that exploit
phages for transfer between bacteria. Satellites can encode defense systems, antibiotic …
phages for transfer between bacteria. Satellites can encode defense systems, antibiotic …
Hijackers, hitchhikers, or co-drivers? The mysteries of mobilizable genetic elements
Mobile genetic elements shape microbial gene repertoires and populations. Recent results
reveal that many, possibly most, microbial mobile genetic elements require helpers to …
reveal that many, possibly most, microbial mobile genetic elements require helpers to …
Tail assembly interference is a common strategy in bacterial antiviral defenses
Many bacterial immune systems recognize phage structural components to activate antiviral
responses, without inhibiting the function of the phage component. These systems can be …
responses, without inhibiting the function of the phage component. These systems can be …
Induction mechanisms and strategies underlying interprophage competition during polylysogeny
JE Silpe, OP Duddy, BL Bassler - PLoS pathogens, 2023 - journals.plos.org
Phages play central roles in shaping bacterial community biology. For example, lytic
phages, by eliminating particular subpopulations of bacteria, control the composition of …
phages, by eliminating particular subpopulations of bacteria, control the composition of …
Phage‐Inducible Chromosomal Islands as a Diagnostic Platform to Capture and Detect Bacterial Pathogens
R Ibarra‐Chávez, J Reboud, JR Penadés… - Advanced …, 2023 - Wiley Online Library
Phage‐inducible chromosomal islands (PICIs) are a family of phage satellites that hijack
phage components to facilitate their mobility and spread. Recently, these genetic constructs …
phage components to facilitate their mobility and spread. Recently, these genetic constructs …
Phage-inducible chromosomal islands promote genetic variability by blocking phage reproduction and protecting transductants from phage lysis
Phage-inducible chromosomal islands (PICIs) are a widespread family of highly mobile
genetic elements that disseminate virulence and toxin genes among bacterial populations …
genetic elements that disseminate virulence and toxin genes among bacterial populations …