Cellular communication through extracellular vesicles and lipid droplets

I Amarasinghe, W Phillips, AF Hill… - Journal of …, 2023 - Wiley Online Library
Cellular communication is essential for effective coordination of biological processes. One
major form of intercellular communication occurs via the release of extracellular vesicles …

Organelle interactions compartmentalize hepatic fatty acid trafficking and metabolism

CP Najt, S Adhikari, TD Heden, W Cui, ER Gansemer… - Cell reports, 2023 - cell.com
Organelle interactions play a significant role in compartmentalizing metabolism and
signaling. Lipid droplets (LDs) interact with numerous organelles, including mitochondria …

Lipid droplet-derived monounsaturated fatty acids traffic via PLIN5 to allosterically activate SIRT1

CP Najt, SA Khan, TD Heden, BA Witthuhn, M Perez… - Molecular cell, 2020 - cell.com
Lipid droplets (LDs) provide a reservoir for triacylglycerol storage and are a central hub for
fatty acid trafficking and signaling in cells. Lipolysis promotes mitochondrial biogenesis and …

Methods for Lipid Droplet Biophysical Characterization in Flaviviridae Infections

AS Martins, IC Martins, NC Santos - Frontiers in Microbiology, 2018 - frontiersin.org
Lipid droplets (LDs) are intracellular organelles for neutral lipid storage, originated from the
endoplasmic reticulum. They play an essential role in lipid metabolism and cellular …