Cyclooxygenases (COXs) catalyze the rate-limiting step in the production of prostaglandins,
bioactive compounds involved in processes such as fever and sensitivity to pain, and are the …

Many flavoproteins catalyze the oxidation of primary and secondary amines, with the transfer
of a hydride equivalent from a carbon–nitrogen bond to the flavin cofactor. Most of these …

The second edition of Structure in Protein Chemistry showcases the latest developments
and innovations in the field of protein structure analysis and prediction. The book begins by …

Flavoproteins are ubiquitous redox proteins that are involved in many biological processes.
In the majority of flavoproteins, the flavin cofactor is tightly but noncovalently bound …

Lactate utilization endows microbes with the ability to use lactate as a carbon source.
Lactate oxidizing enzymes play key roles in the lactate utilization pathway. Various types of …

The present understanding of the mechanisms by which flavoproteins oxidize amino acid or
hydroxy acids to the respective imino or keto acids is reviewed. The observation that many of …

l-Lactate oxidase (LOX) from Aerococcus viridans is a member of the α-hydroxyacid-oxidase
flavoenzyme family. We have determined the three-dimensional structure of LOX and …

This review article describes the occurrence, general properties, and substrate specificity of
the flavoenzymes belonging to the glucose-methanol-choline oxidoreductase superfamily …

Human glycolate oxidase (GO) catalyzes the FMN-dependent oxidation of glycolate to
glyoxylate and glyoxylate to oxalate, a key metabolite in kidney stone formation. We report …

Mandelic acid and its derivatives are an important class of chemical synthetic blocks, which
is widely used in drug synthesis and stereochemistry research. In nature, mandelic acid …