Myeloperoxidase–A bridge linking inflammation and oxidative stress with cardiovascular disease
G Ndrepepa - Clinica chimica acta, 2019 - Elsevier
Myeloperoxidase (MPO) is a member of the superfamily of heme peroxidases that is mainly
expressed in neutrophils and monocytes. MPO-derived reactive species play a key role in …
expressed in neutrophils and monocytes. MPO-derived reactive species play a key role in …
The role of myeloperoxidase in biomolecule modification, chronic inflammation, and disease
MJ Davies, CL Hawkins - Antioxidants & redox signaling, 2020 - liebertpub.com
Significance: The release of myeloperoxidase (MPO) by activated leukocytes is critical in
innate immune responses. MPO produces hypochlorous acid (HOCl) and other strong …
innate immune responses. MPO produces hypochlorous acid (HOCl) and other strong …
Unraveling the complexities of the HDL lipidome1
A Kontush, M Lhomme, MJ Chapman - Journal of lipid research, 2013 - ASBMB
Plasma high density lipoproteins (HDL) are small, dense, protein-rich particles compared
with other lipoprotein classes; roughly half of total HDL mass is accounted for by lipid …
with other lipoprotein classes; roughly half of total HDL mass is accounted for by lipid …
Myeloperoxidase: molecular mechanisms of action and their relevance to human health and disease
BS Van der Veen, MPJ de Winther… - Antioxidants & redox …, 2009 - liebertpub.com
Abstract 2900 Myeloperoxidase (MPO) is a heme-containing peroxidase abundantly
expressed in neutrophils and to a lesser extent in monocytes. Enzymatically active MPO …
expressed in neutrophils and to a lesser extent in monocytes. Enzymatically active MPO …
Myeloperoxidase and cardiovascular disease
SJ Nicholls, SL Hazen - Arteriosclerosis, thrombosis, and vascular …, 2005 - Am Heart Assoc
Myeloperoxidase (MPO) is a leukocyte-derived enzyme that catalyzes the formation of a
number of reactive oxidant species. In addition to being an integral component of the innate …
number of reactive oxidant species. In addition to being an integral component of the innate …
[HTML][HTML] Myeloperoxidase: Growing importance in cancer pathogenesis and potential drug target
P Valadez-Cosmes, S Raftopoulou, ZN Mihalic… - Pharmacology & …, 2022 - Elsevier
Myeloperoxidase is a heme-peroxidase which makes up approximately 5% of the total dry
cell weight of neutrophils where it is predominantly found in the primary (azurophilic) …
cell weight of neutrophils where it is predominantly found in the primary (azurophilic) …
[HTML][HTML] Plasmalogens, platelet-activating factor and beyond–Ether lipids in signaling and neurodegeneration
F Dorninger, S Forss-Petter, I Wimmer, J Berger - Neurobiology of disease, 2020 - Elsevier
Glycerol-based ether lipids including ether phospholipids form a specialized branch of lipids
that in mammals require peroxisomes for their biosynthesis. They are major components of …
that in mammals require peroxisomes for their biosynthesis. They are major components of …
The roles of myeloperoxidase in coronary artery disease and its potential implication in plaque rupture
N Teng, GJ Maghzal, J Talib, I Rashid, AK Lau… - Redox …, 2017 - Taylor & Francis
Atherosclerosis is the main pathophysiological process underlying coronary artery disease
(CAD). Acute complications of atherosclerosis, such as myocardial infarction, are caused by …
(CAD). Acute complications of atherosclerosis, such as myocardial infarction, are caused by …
Myeloperoxidase: a target for new drug development?
E Malle, PG Furtmüller, W Sattler… - British journal of …, 2007 - Wiley Online Library
Myeloperoxidase (MPO), a member of the haem peroxidase‐cyclooxygenase superfamily, is
abundantly expressed in neutrophils and to a lesser extent in monocytes and certain type of …
abundantly expressed in neutrophils and to a lesser extent in monocytes and certain type of …
Uremia alters HDL composition and function
M Holzer, R Birner-Gruenberger… - Journal of the …, 2011 - journals.lww.com
Functional impairment of HDL may contribute to the excess cardiovascular mortality
experienced by patients with renal disease, but the effect of advanced renal disease on the …
experienced by patients with renal disease, but the effect of advanced renal disease on the …