Background Cancer is a global health challenge, it impacts the quality of life and its
treatment is associated with several side effects. Resistance of the cancer cells to the …

Heterocyclic compounds hold a pivotal place in medicinal chemistry due to their wide range
of biological activities and thus, are exhaustively explored in the field of drug design and …

This review article proposes a comprehensive report of the design strategies engaged in the
development of various sulfur‐bearing cytotoxic agents. The outcomes of various studies …

Thienopyrimidine scaffold is a fused heterocyclic ring system that structurally can be
considered as adenine, the purine base that is found in both DNA and RNA-bioisosteres …

To explore anticancer and antioxidant agents with improved potency, we synthesized a
series of amide linked 1, 4-disubstituted 1, 2, 3-triazoles through click chemistry approach …

Research on thymidylate synthase inhibitors has been a hot spot for anticancer drug
development. Here, based on the structures and pharmacological properties of two types of …

A series of forty α-substituted chalcones were synthesized and screened for their
antiproliferative activities against HCT116 (colorectal) and HCC1954 (breast) cancer cell …

Five oxovanadium (IV) complexes were synthesized using acetyl-and benzoylacetone-S-
alkyl-thiosemicarbazones (alkyl= methyl, ethyl, propyl or butyl) and salicylaldehyde …

Naphthol or β-naphthol is an important starting material that has drawn great attention in
various organic transformations because of its attributes, such as low cost, easy to handle …

Thiophenes are one of the abundantly found heterocyclic ring systems in many biologically
active compounds. Moreover, various substituted thiophenes exert numerous …