Abstract Type V and VI CRISPR enzymes are RNA-guided, DNA and RNA-targeting
effectors that allow specific gene knockdown. Cas12 and Cas13 are CRISPR proteins that …

The Chinese hamster ovary (CHO) cell line is a well-established platform for the production
of biopharmaceuticals due to its ability to express complex therapeutic proteins with human …

Resumen SAFARI, Fatemeh y AKBARI, Bahman. Knockout of caspase-7 gene improves the
expression of recombinant protein in CHO cell line through the cell cycle arrest in G2/M …

For industrial production of recombinant protein biopharmaceuticals, Chinese hamster ovary
(CHO) cells represent the most widely adopted host cell system, owing to their capacity to …

Type1 Non-specific Lipid Transfer Protein (CsLTP1) from Citrus sinensis is a small cationic
protein possessing a long tunnel-like hydrophobic cavity. CsLTP1 performing membrane …

Two genome editions have resulted in the CHO cell line 4BGD with homozygous knockouts
of the BAK1, BAX, DHFR and GLUL genes, and overexpression of the BCL2 and BECN1 …

Background: CHO cells are preferred for producing biopharmaceuticals, and genome
editing technologies offer opportunities to enhance recombinant protein production …

При помощи двух операций геномного редактирования получена линия клеток CHO-
4BGD с гомозиготными нокаутами генов BAK1, BAX, DHFR, GLUL и оверэкспрессией …

Primeiramente a DEUS, que esteve presente em todos os momentos de nossas vidas, que
proporcionou mais uma vitória e nos manteve seguros nessa grande aventura, chamada …

Changes in the expression of the Casp7 gene in the liver of rats under the influence of
alcohol were evaluated. White outbred male rats were used in the work. Under the …