Fluorouracil (5-FU) is an essential component of systemic chemotherapy for colorectal
cancer (CRC) in the palliative and adjuvant settings. Over the past four decades, several …

Reactive oxygen species (ROS) are by‐products of normal cell activity. They are produced
in many cellular compartments and play a major role in signaling pathways. Overproduction …

Although 5-fluorouracil (5-FU)-based chemotherapy is the major treatment for colorectal
cancer, it has disadvantages such as systemic toxicity, lack of effectiveness and selectivity …

Simple Summary Tumor growth in solid cancers requires adequate nutrient and oxygen
supply, provided by blood vessels created by angiogenesis. Numerous studies have …

Drug resistance is a major hurdle in cancer treatment and a key cause of poor prognosis.
Epitranscriptomics and epiproteomics are crucial in cell proliferation, migration, invasion …

Genetic, developmental, biochemical, and environmental variables interact intricately to
produce sex differences. The significance of sex differences in cancer susceptibility is being …

Gastric adenocarcinoma is one of the most common types of cancer worldwide, with an
incidence of a million new cases annually. In addition to having a high mortality rate due to …

Identifying a strategy with strong efficacy against non-inflamed tumours is vital in cancer
immune therapy. ERY974 is a humanized IgG4 bispecific T cell-redirecting antibody that …

Recently, we demonstrated that sterile α motif and HD domain containing protein 1
(SAMHD1) is a major barrier in acute myelogenous leukemia (AML) cells to the cytotoxicity …

Thymidine phosphorylase (TP) is an angiogenic enzyme. It plays an important role in
angiogenesis, tumour growth, invasion and metastasis. In current research work, we study …