Endothermy has evolved at least twice, in the precursors to modern mammals and birds. The
most widely accepted explanation for the evolution of endothermy has been selection for …

Thermal acclimation causes the heart of some fish species to undergo significant
remodelling. This includes changes in electrical activity, energy utilization and structural …

Fish and marine invertebrates constitute an important part of the human diet worldwide, and
their muscles are the major edible parts. The muscles are a rich source of proteins, which in …

Ultrastructure, molecular composition and electrophysiological properties of cardiac
myocytes and functional characteristics of the fish heart suggest that cycling of extracellular …

Zebrafish (Danio rerio) are widely used as vertebrate model in developmental genetics and
functional genomics as well as in cardiac structure-function studies. The zebrafish heart has …

The relationship between the strength of contraction and the interval between contractions
was first recognised as an important intrinsic control system of the heart when Bowditch …

ABSTRACT A decrease in environmental temperature represents a challenge to the
cardiovascular system of ectotherms. To gain insight into the cellular changes that occur …

Cold acclimation of zebrafish causes changes to the structure and composition of the heart.
However, little is known of the consequences of these changes on heart function or if these …

This review provides an overview of the evolutionary path to the mammalian heart from the
beginnings of life (about four billion years ago) to the present. Essential tools for cellular …

The cardiac troponin C (cTnC) mutation, L29Q, has been found in a patient with familial
hypertrophic cardiomyopathy. We previously showed that L29, together with neighboring …