The review aims to consolidate research findings on the molecular mechanisms and
virulence and pathogenicity characteristics of coronavirus disease (COVID-19) causative …

Background Gaining further insights into SARS-CoV-2 routes of infection and the underlying
pathobiology of COVID-19 will support the design of rational treatments targeting the life …

The spike protein of SARS-CoV-2 is known to enable viral invasion into human cells through
direct binding to host receptors including ACE2. An alternate entry receptor for the virus was …

The novel coronavirus disease (COVID-19) caused by the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has rapidly evolved into a global pandemic. The …

The recent emergence of highly transmissible SARS-CoV-2 variants illustrates the urgent
need to better understand the molecular details of the virus binding to its host cell and to …

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of
the COVID-19 global pandemic, utilizes the host receptor angiotensin-converting enzyme 2 …

Abstract Angiotensin-converting enzyme 2 (ACE2) is a key host protein by which severe
acute respiratory syndrome coronavirus-2 (SARS-CoV-2) enters and multiplies within cells …

The poor outcome of the coronavirus disease-2019 (COVID-19), caused by SARS-CoV-2, is
associated with systemic hyperinflammatory response and immunopathology. Although …

Abstract Coronavirus disease 2019 (COVID-19) is caused by a new member of the
Coronaviridae family known as severe acute respiratory syndrome coronavirus 2 (SARS …

Two recently published studies published in Science by Daly et al. 1 and Cantuti-Castelvetri
et al. 2 identified neuropilin-1 (NRP1) as an additional cellular mediator which may facilitate …