Methods Literature search was performed using the electronic databases Pubmed, Web of
Knowledge, Embase and Cinahl Complete until December 2019. Cohort and case-control …

Background Glycemic traits—such as hyperinsulinemia, hyperglycemia, and type 2 diabetes—
have been associated with higher colorectal cancer risk in observational studies; however …

Background: Thyroid cancer incidence has increased in many parts of the world since the
1980s, as has the prevalence of obesity. Evidence suggests that people with greater body …

The relationship between hypertension and risk of colorectal cancer (CRC) is unclear. This
meta-analysis aims to explore the association between them. Six databases were searched …

Colorectal cancer (CRC) has become a major health concern in China due to its increasing
incidence and mortality. This study aimed to clarify the relationship between tumor locations …

Background: Dyslipidemia is closely associated with metabolic syndrome, a known risk
factor for colorectal cancer. However, the association of dyslipidemia with colorectal cancer …

Abstract Purpose Recent Mendelian randomization (MR) studies derived inconsistent results
of blood lipids' effect on colorectal cancer, and whether the blood lipids' effect on colon and …

Obesity and metabolic dysfunction are implicated in colorectal cancer development. Appetite-
regulating gut hormones might have a role in colorectal cancer risk. We investigated …

Background Colorectal cancer (CRC) is the third most common cancer and leading cause of
cancer-related deaths worldwide. Aberrant cellular metabolism is a hallmark of cancer cells …

Body fatness increases the risk of colorectal cancer (CRC). Insulin resistance and altered
adipokines are potential mechanisms, but previous biomarker studies have been …