Targeting diffuse midline gliomas: The promise of focused ultrasound-mediated blood-brain barrier opening
Diffuse midline gliomas (DMGs), including diffuse intrinsic pontine glioma, have among the
highest mortality rates of all childhood cancers, despite recent advancements in cancer …
highest mortality rates of all childhood cancers, despite recent advancements in cancer …
Cardiac PET imaging of ATP binding cassette (ABC) transporters: opportunities and challenges
W Liu, P Mossel, V Schwach, RHJA Slart, G Luurtsema - Pharmaceuticals, 2023 - mdpi.com
Adenosine triphosphate binding cassette (ABC) transporters are a broad family of
membrane protein complexes that use energy to transport molecules across cells and/or …
membrane protein complexes that use energy to transport molecules across cells and/or …
Head-to-head comparison of (R)-[11C]verapamil and [18F]MC225 in non-human primates, tracers for measuring P-glycoprotein function
Purpose P-glycoprotein (P-gp) function is altered in several brain disorders; thus, it is of
interest to monitor the P-gp function in vivo using PET.(R)-[11C] verapamil is considered the …
interest to monitor the P-gp function in vivo using PET.(R)-[11C] verapamil is considered the …
The ATP-Binding Cassette Transporter-Mediated Efflux Transport of Ganciclovir at the Blood–Brain Barrier
Y Shan, Y Cen, X Xu, P Li, J Chen, Z Nie… - European Journal of Drug …, 2024 - Springer
Abstract Background and Objective Recent studies have highlighted the key role of the ATP-
binding cassette (ABC) transporters, including the P-glycoprotein (P-gp), the breast cancer …
binding cassette (ABC) transporters, including the P-glycoprotein (P-gp), the breast cancer …
Head to head comparison of (R)-[11C] verapamil and [18F] MC225 in non-human primates, tracers for measuring P-glycoprotein function
Purpose P-glycoprotein (P-gp) function is altered in several brain disorders; thus, it is of
interest to monitor the P-gp function in vivo using PET.(R)-[11 C] verapamil is considered as …
interest to monitor the P-gp function in vivo using PET.(R)-[11 C] verapamil is considered as …