The recent outbreak of coronavirus disease 2019 (COVID-19) highlights an urgent need for
therapeutics. Through a series of drug repurposing screening campaigns, niclosamide, an …

The development of effective antiviral therapy for COVID-19 is critical for those awaiting
vaccination, as well as for those who do not respond robustly to vaccination. This review …

The development of new and effective antibacterial drugs to treat multi-drug resistant (MDR)
bacteria, especially Gram-negative (G− ve) pathogens, is acknowledged as one of the …

Breast cancer is the most common cancer among women and is typically managed through
surgery, radiation therapy, and chemotherapy. However, chemotherapy drugs often lack …

The dual functions of TMEM16F as Ca2+-activated ion channel and lipid scramblase raise
intriguing questions regarding their molecular basis. Intrigued by the ability of the FDA …

There is a rapidly expanding literature on the in vitro antiviral activity of drugs that may be
repurposed for therapy or chemoprophylaxis against severe acute respiratory syndrome …

Multidrug-resistant (MDR) pathogens pose a well-recognized global health threat that
demands effective solutions; the situation is deemed a global priority by the World Health …

The major impact produced by the severe acute respiratory syndrome coronavirus 2 (SARS‑
CoV‑2) focused many researchers attention to find treatments that can suppress …

The properties and characteristics of calix [n] arenes are described, as well as their capacity
to form amphiphilic assemblies by means of the design of synthetic macrocycles with a …

Importance Oral anthelmintic niclosamide has potent in vitro antiviral activity against SARS-
CoV-2. Repurposed niclosamide could be a safe and efficacious COVID-19 therapy …