Structure-based virtual screening, molecular docking, and molecular dynamics simulation of VEGF inhibitors for the clinical treatment of ovarian cancer
Vascular endothelial growth factor (VEGF) and its receptor play an important role both in
physiologic and pathologic angiogenesis, which is identified in ovarian cancer progression …
physiologic and pathologic angiogenesis, which is identified in ovarian cancer progression …
Structure-based virtual screening, molecular docking, molecular dynamics simulation and pharmacokinetic modelling of cyclooxygenase-2 (COX-2) inhibitor for the …
Colorectal cancer is the third most frequent cause of cancer worldwide and is more
prevalent in older individuals of all ages. The recent statistics from World Health …
prevalent in older individuals of all ages. The recent statistics from World Health …
Virtual screening for potential phytobioactives as therapeutic leads to inhibit NQO1 for selective anticancer therapy
B Shreevatsa, C Dharmashekara, VH Swamy… - Molecules, 2021 - mdpi.com
NAD (P) H: quinone acceptor oxidoreductase-1 (NQO1) is a ubiquitous flavin adenine
dinucleotide-dependent flavoprotein that promotes obligatory two-electron reductions of …
dinucleotide-dependent flavoprotein that promotes obligatory two-electron reductions of …
Unveiling the ESR1 conformational stability and screening potent inhibitors for breast cancer treatment
Background: The current study recognizes the significance of estrogen receptor alpha (ERα)
as a member of the nuclear receptor protein family, which holds a central role in the …
as a member of the nuclear receptor protein family, which holds a central role in the …
Synthesis, crystal structure, hirshfeld surface analysis, molecular docking and molecular dynamics studies of novel olanzapinium 2, 5-dihydroxybenzoate as potential …
V Natchimuthu, M Abdalla, M Yadav… - Journal of …, 2022 - Taylor & Francis
The antipsychotic drug Olanzapine was crystallized with aromatic acid, 2, 5-
dihydroxybenzoic acid in isopropyl alcohol by slow evaporation which led to the formation of …
dihydroxybenzoic acid in isopropyl alcohol by slow evaporation which led to the formation of …
Structural insights into conformational stability of ESR1 and structure base screening of new potent inhibitor for the treatment of Breast Cancer
Estrogen receptor alpha (ERα), a nuclear receptor protein encoded by the estrogen
receptor1 (ESR1) gene, is an important biomarker in breast cancer diagnosis. Any …
receptor1 (ESR1) gene, is an important biomarker in breast cancer diagnosis. Any …
Multi-scale Cleaner Analysis of Chemical Looping Gasification Coupled Coal Pyrolysis Process.
Z Cui, C Fan, W Tian, Q Guo - CET Journal-Chemical …, 2020 - search.ebscohost.com
Coal is one of combustion fuel sources that occupies an important position in the world
energy resource structure. Coal pyrolysis is a very complex process involving myriad …
energy resource structure. Coal pyrolysis is a very complex process involving myriad …