Positron emission tomography (PET) uses radioactive tracers and enables the functional
imaging of several metabolic processes, blood flow measurements, regional chemical …

Abstract Rudolph Virchow (1821–1902) recognized inflammation in histological
preparations of coronary arteries and proposed that inflammation plays a causal role in …

Immunotherapy, specifically the introduction of immune checkpoint inhibitors, has
transformed the treatment of cancer, enabling long-term tumour control even in individuals …

Understanding the natural history of coronary artery atherosclerosis is necessary to
determine prognosis and prescribe effective therapies. Traditional management of coronary …

Inflammation is a pivotal driver of atherosclerotic plaque progression and rupture and is a
target for identifying vulnerable plaques. However, challenges arise with the current in vivo …

With this document, we provide a standard for PET/(diagnostic) CT imaging procedures in
cardiovascular diseases that are inflammatory, infective, infiltrative, or associated with …

Macrophages are ubiquitous cells that reside in all major tissues. Counter to long-held
beliefs, we now know that resident macrophages in many organs are seeded during …

The detection and characterization of coronary artery stenosis and atherosclerosis using
imaging tools are key for clinical decision-making in patients with known or suspected …

Importance Recurrent coronary events in patients with recent myocardial infarction remain a
major clinical problem. Noninvasive measures of coronary atherosclerotic disease activity …

Targeting residual cardiovascular risk in primary and secondary prevention, would allow
deployment of novel therapeutic agents, facilitating precision medicine. For example …