The birth certificate for endocrinology was Bayliss' and Starling's demonstration in 1902 that
regulation of bodily functions is not only neuronal, but due also to blood-borne messengers …

It is exactly a century since the gastric hormone gastrin was first described as a blood-borne
regulator of gastric acid secretion. The identities of the main active forms of the hormone (the …

Ghrelin is a 28 aa gastric peptide, recently identified as a natural ligand of the growth
hormone secretagogue receptor (orphan receptor distinct from the receptor for growth …

Both ghrelin and obestatin are derived from preproghrelin by post-translational processing.
We have morphologically characterized the cells that produce obestatin and ghrelin in new …

Ghrelin, a recently discovered peptide hormone, is produced by endocrine cells in the
stomach, the so-called A-like cells. Ghrelin binds to the growth hormone (GH) secretagogue …

Gastric acid secretion is under nervous and hormonal control. Gastrin, the major circulating
stimulus of acid secretion, probably does not stimulate the parietal cells directly but acts to …

The physiology of gastric acid secretion is one of the earliest subjects in medical literature
and has been continuously studied since 1833. Starting with the notion that neural …

▪ Abstract The regulation of gastric acid secretion is achieved in the periphery by interplay
between three major gastric endocrine cells: the enterochromaffin-like (ECL) cell, the gastrin …

BACKGROUND & AIMS:: Histamine, gastrin, and acetylcholine are known to be the primary
secretagogues of gastric acid secretion, but how the roles are shared among these …

Background & Aims Enterochromaffin-like (ECL) cells in the stomach express
gastrin/cholecystokinin 2 receptor CCK2R and are known to expand under …