Ester coupling reactions–an enduring challenge in the chemical synthesis of bioactive natural products

M Tsakos, ES Schaffert, LL Clement… - Natural product …, 2015 - pubs.rsc.org
Covering: up to 2014 In this review we investigate the use of complex ester fragment
couplings within natural product total synthesis campaigns. We first outline the different …

Applications of Yamaguchi method to esterification and macrolactonization in total synthesis of bioactive natural products

S Majhi - ChemistrySelect, 2021 - Wiley Online Library
Yamaguchi protocol provides functionalized esters regioselectively from carboxylic acids
and alcohols employing 2, 4, 6‐trichlorobenzoyl chloride as the condensation reagent in the …

[HTML][HTML] A solvent-reagent selection guide for Steglich-type esterification of carboxylic acids

A Jordan, KD Whymark, J Sydenham, HF Sneddon - Green Chemistry, 2021 - pubs.rsc.org
The Steglich esterification is a widely employed method for the formation of esters under
mild conditions. A number of issues regarding the sustainability of this transformation have …

In situ activation of STING pathway with polymeric SN38 for cancer chemoimmunotherapy

J Zhao, S Ma, Y Xu, X Si, H Yao, Z Huang, Y Zhang… - Biomaterials, 2021 - Elsevier
STING (stimulator of interferon genes) signaling pathway has attracted considerable
attention in cancer immunotherapy due to its capacity to boost vigorous antitumor immunity …

Bio-functionalization of metal–organic frameworks by covalent protein conjugation

S Jung, Y Kim, SJ Kim, TH Kwon, S Huh… - Chemical …, 2011 - pubs.rsc.org
Bioconjugation of functional proteins onto metal–organic frameworks (MOFs) has been
achieved using activation of pendent linking groups of the organic linkers on the surface of …

[HTML][HTML] The intriguing molecular dynamics of Cer [EOS] in rigid skin barrier lipid layers requires improvement of the model

F Fandrei, T Havrišák, L Opálka, O Engberg… - Journal of Lipid …, 2023 - ASBMB
Omega-O-acyl ceramides such as 32-linoleoyloxydotriacontanoyl sphingosine (Cer [EOS])
are essential components of the lipid skin barrier, which protects our body from excessive …

Efficient and controllably selective preparation of esters using uronium-based coupling agents

JAK Twibanire, TB Grindley - Organic letters, 2011 - ACS Publications
Carboxylic acid esters can be prepared in excellent yields at room temperature from an acid
and either a phenol or an aliphatic alcohol using the peptide coupling reagents, TBTU …

Amidation and esterification of carboxylic acids with amines and phenols by N, N′-diisopropylcarbodiimide: A new approach for amide and ester bond formation in …

N Fattahi, M Ayubi, A Ramazani - Tetrahedron, 2018 - Elsevier
The present study reports the successful synthesis of two important and abundant functional
groups" ester and amide" by N, N′-diisopropylcarbodiimide (DIC) in water as a green …

Palladium-Catalyzed Decarbonylative Sonogashira Coupling of Terminal Alkynes with Carboxylic Acids

X Li, L Liu, T Huang, Z Tang, C Li, W Li, T Zhang… - Organic …, 2021 - ACS Publications
A direct decarbonylative Sonogashira coupling of terminal alkynes with carboxylic acids was
achieved through palladium catalysis. This reaction did not use overstoichiometric oxidants …

Copper (II)-catalyzed ortho-functionalization of 2-arylpyridines with acyl chlorides

W Wang, C Pan, F Chen, J Cheng - Chemical Communications, 2011 - pubs.rsc.org
Copper( ii )-catalyzed ortho -functionalization of 2-arylpyridines with acyl chlorides -
Chemical Communications (RSC Publishing) DOI:10.1039/C0CC05557C Royal Society of …