The blood-brain barrier (BBB) plays a vital role in regulating the trafficking of fluid, solutes
and cells at the blood-brain interface and maintaining the homeostatic microenvironment of …

Nowadays, a large population around the world, especially the elderly, suffers from
neurological inflammatory and degenerative disorders/diseases. Current drug delivery …

The safe and effective delivery of drugs is a major obstacle in the treatment of ischemic
stroke. Exosomes hold great promise as an endogenous drug delivery nanosystem for the …

Ischemic stroke remains a major cause of death, and anti-inflammatory strategies hold great
promise for preventing major brain injury during reperfusion. In the past decade, stem cell …

The blood-brain barrier (BBB) is formed by the endothelial cells of cerebral microvessels,
providing a dynamic interface between the peripheral circulation and the central nervous …

There is an urgent need for improved diagnostics and therapeutics for acute ischemic stroke.
This is the focus of numerous research projects involving in vitro studies, animal models and …

The blood–brain barrier (BBB) is formed primarily to protect the brain microenvironment from
the influx of plasma components, which may disturb neuronal functions. The BBB is a …

Stroke causes cell death but also birth and migration of new neurons within sites of ischemic
damage. The cellular environment that induces neuronal regeneration and migration after …

Cerebral microvessels have a unique ultrastructure form, which allows for the close
relationship of the endothelium and blood elements to the neurons they serve, via …

Vascular endothelial growth factors (VEGFs) have been shown to participate in
atherosclerosis, arteriogenesis, cerebral edema, neuroprotection, neurogenesis …