Role of capsid proteins in parvoviruses infection

M Tu, F Liu, S Chen, M Wang, A Cheng - Virology journal, 2015 - Springer
The parvoviruses are widely spread in many species and are among the smallest DNA
animal viruses. The parvovirus is composed of a single strand molecule of DNA wrapped …

Nuclear entry and egress of parvoviruses

S Mattola, V Aho… - Molecular …, 2022 - Wiley Online Library
Parvoviruses are small non‐enveloped single‐stranded DNA viruses, which depend on host
cell nuclear transcriptional and replication machinery. After endosomal exposure of nuclear …

Equine parvovirus-hepatitis in China: Characterization of its genetic diversity and evidence for natural recombination events between the Chinese and American …

G Lu, L Wu, J Ou, S Li - Frontiers in Veterinary Science, 2020 - frontiersin.org
Equine parvovirus-hepatitis (EqPV-H) was first reported in a horse that died of equine serum
hepatitis in the USA in 2018, and was determined having a strong association with equine …

Protoparvovirus Cell Entry

C Ros, N Bayat, R Wolfisberg, JM Almendral - Viruses, 2017 - mdpi.com
The Protoparvovirus (PtPV) genus of the Parvoviridae family of viruses includes important
animal pathogens and reference molecular models for the entire family. Some virus …

Structural analysis of a temperature-induced transition in a viral capsid probed by HDX-MS

M Van de Waterbeemd, A Llauró, J Snijder… - Biophysical …, 2017 - cell.com
Icosahedral viral capsids are made of a large number of symmetrically organized protein
subunits whose local movements can be essential for infection. In the capsid of the minute …

[HTML][HTML] Viral targeting of glioblastoma stem cells with patient-specific genetic and post-translational p53 deregulations

J Gil-Ranedo, C Gallego-García, JM Almendral - Cell reports, 2021 - cell.com
Cancer therapy urges targeting of malignant subsets within self-renewing heterogeneous
stem cell populations. We dissect the genetic and functional heterogeneity of human …

Structural basis for biologically relevant mechanical stiffening of a virus capsid by cavity-creating or spacefilling mutations

P Guerra, A Valbuena, J Querol-Audí, C Silva… - Scientific reports, 2017 - nature.com
Recent studies reveal that the mechanical properties of virus particles may have been
shaped by evolution to facilitate virus survival. Manipulation of the mechanical behavior of …

Amino acid side chains buried along intersubunit interfaces in a viral capsid preserve low mechanical stiffness associated with virus infectivity

PJP Carrillo, M Medrano, A Valbuena… - ACS …, 2017 - ACS Publications
Single-molecule experimental techniques and theoretical approaches reveal that important
aspects of virus biology can be understood in biomechanical terms at the nanoscale. A …

Classic nuclear localization signals and a novel nuclear localization motif are required for nuclear transport of porcine parvovirus capsid proteins

M Boisvert, V Bouchard-Lévesque… - Journal of …, 2014 - Am Soc Microbiol
Nuclear targeting of capsid proteins (VPs) is important for genome delivery and precedes
assembly in the replication cycle of porcine parvovirus (PPV). Clusters of basic amino acids …

[HTML][HTML] VEGF—Virus Interactions: Pathogenic Mechanisms and Therapeutic Applications

C Sánchez-Martínez, E Grueso, T Calvo-López… - Cells, 2024 - mdpi.com
Many types of viruses directly or indirectly target the vascular endothelial growth factor
(VEGF) system, which is a central regulator of vasculogenesis and angiogenesis in …