NLRP3 inflammasome and its inhibitors: a review

BZ Shao, ZQ Xu, BZ Han, DF Su, C Liu - Frontiers in pharmacology, 2015 - frontiersin.org
Inflammasomes are newly recognized, vital players in innate immunity. The best
characterized is the NLRP3 inflammasome, so-called because the NLRP3 protein in the …

Familial Mediterranean fever, review of the literature

M Alghamdi - Clinical rheumatology, 2017 - Springer
Familial Mediterranean fever (FMF) is the most common monogenic periodic fever syndrome
and characterized by recurrent episodes of fever, serositis, arthritis, dermal manifestations …

A narrative review on the role of cytokines in the pathogenesis and treatment of familial Mediterranean fever: an emphasis on pediatric cases

A Chaaban, H Yassine, R Hammoud, R Kanaan… - Frontiers in …, 2024 - frontiersin.org
Familial Mediterranean Fever (FMF) is a hereditary autoinflammatory disease characterized
by an early onset of recurrent fever and serositis episodes. FMF is caused by mutations in …

Familial Mediterranean fever: the molecular pathways from stress exposure to attacks

C Korkmaz, DU Cansu, GB Cansu - Rheumatology, 2020 - academic.oup.com
FMF is an autoinflammatory disease characterized by recurrent attacks and increased IL-1
synthesis owing to activation of the pyrin inflammasome. Although knowledge of the …

NLRP13 inflammasome complex is hypermethylated in familial Mediterranean fever and global methylation correlates with the disease severity

FY Caldiran, K Deveci, E Cacan - Annals of Human Genetics, 2023 - Wiley Online Library
Familial Mediterranean fever (FMF) is an autoinflammatory disease caused by variations in
the MEFV gene, which encodes the pyrin protein, a member of the inflammasomes. Despite …

Dynamics of inflammatory response in autoinflammatory disorders: autonomous and hyperinflammatory states

A Gül - Frontiers in Immunology, 2018 - frontiersin.org
Autoinflammatory diseases were originally defined as a group of monogenic disorders
associated with seemingly unprovoked inflammatory episodes mediated mainly by the …

Canakinumab treatment in children with familial Mediterranean fever: report from a single center

F Yazılıtaş, Ö Aydoğ, SG Özlü, EK Çakıcı… - Rheumatology …, 2018 - Springer
Familial Mediterranean fever (FMF), the most common hereditary autoinflammatory disorder
is characterized by recurrent episodes of fever, serositis, arthritis. The major long-term result …

[HTML][HTML] The importance of Mediterranean fever gene in familial Mediterranean fever

DY Kehribar, M Özgen - European Journal of Rheumatology, 2020 - ncbi.nlm.nih.gov
Objective Familial Mediterranean fever (FMF) is the most common autoinflammatory disease
characterized by recurrent serositis attacks and fever. The discovery of the Mediterranean …

The genetic heterogeneity among different mouse strains impacts the lung injury potential of multiwalled carbon nanotubes

X Wang, YP Liao, D Telesca, CH Chang, T Xia, AE Nel - Small, 2017 - Wiley Online Library
Genetic variation constitutes an important variable impacting the susceptibility to inhalable
toxic substances and air pollutants, as reflected by epidemiological studies in humans and …

Altered expression of miR-17 and miR-148b in pediatric familial mediterranean fever patients

MF Sokkar, GN Eldeen, RS Lotfy, MM Kobesiy… - Clinical …, 2024 - Springer
Familial Mediterranean fever (FMF) is a recessively inherited autoinflammatory disorder with
wide phenotypic variation that has been observed among individuals who have the same …