Decades of neurobiological research have disclosed the diverse manners in which the
response properties of neurons are dynamically modulated to support adaptive cognitive …

Cortical networks are composed of glutamatergic excitatory projection neurons and local
GABAergic inhibitory interneurons that gate signal flow and sculpt network dynamics …

The term 'stress'–coined in 1936–has many definitions, but until now has lacked a
theoretical foundation. Here we present an information-theoretic approach–based on the …

Cortical gain regulation allows neurons to respond adaptively to changing inputs. Neural
gain is modulated by internal and external influences, including attentional and arousal …

Inhibitory interneurons are essential components of the neural circuits underlying various
brain functions. In the neocortex, a large diversity of GABA (γ-aminobutyric acid) …

The vast computational power of the brain has traditionally been viewed as arising from the
complex connectivity of neural networks, in which an individual neuron acts as a simple …

Most synaptic inputs are made onto the dendritic tree. Recent work has shown that dendrites
play an active role in transforming synaptic input into neuronal output and in defining the …

Computational models based on diffusion processes have been proposed to account for
human decision‐making behaviour in a variety of tasks. The basic idea is that the brain …

Recent anatomical and functional characterization of cortical inhibitory interneurons has
highlighted the diverse computations supported by different subtypes of interneurons …

Many cortical neurons combine the information ascending and descending the cortical
hierarchy. In the classical view, this information is combined nonlinearly to give rise to a …