DNA methylation is one of the best characterized epigenetic modifications. In mammals it is
involved in various biological processes including the silencing of transposable elements …

Research efforts during the past decades have provided intriguing evidence suggesting that
stressful experiences during pregnancy exert long-term consequences on the future mental …

Genome-wide DNA methylation reprogramming occurs in mouse primordial germ cells
(PGCs) and preimplantation embryos, but the precise dynamics and biological outcomes are …

DNA methylation is one of the best-characterized epigenetic modifications and has been
implicated in numerous biological processes, including transposable element silencing …

Epigenetic marking systems confer stability of gene expression during mammalian
development. Genome-wide epigenetic reprogramming occurs at stages when …

Epigenetic reprogramming including demethylation of DNA occurs in mammalian primordial
germ cells (PGCs) and in early embryos, and is important for the erasure of imprints and …

Epigenetic reprogramming, characterized by loss of cytosine methylation and histone
modifications, occurs during mammalian development in primordial germ cells (PGCs), yet …

A variety of experimental and epidemiological studies lend support to the Developmental
Origin of Health and Disease (DOHaD) concept. Yet, the actual mechanisms accounting for …

Cells of the early mammalian embryo, including pluripotent embryonic stem (ES) cells and
primordial germ cells (PGCs), are epigenetically dynamic and heterogeneous. During early …

Environmental influence on developmental plasticity impacts a wide diversity of animal life
from insects to humans. We now understand the epigenetic basis for many of these altered …