[HTML][HTML] Human gut-associated lymphoid tissues (GALT); diversity, structure, and function

UM Mörbe, PB Jørgensen, TM Fenton, N von Burg… - Mucosal …, 2021 - Elsevier
Gut-associated lymphoid tissues (GALT) are the key antigen sampling and adaptive immune
inductive sites within the intestinal wall. Human GALT includes the multi-follicular Peyer's …

Meta-analysis of leukocyte diversity in atherosclerotic mouse aortas

A Zernecke, H Winkels, C Cochain… - Circulation …, 2020 - Am Heart Assoc
The diverse leukocyte infiltrate in atherosclerotic mouse aortas was recently analyzed in 9
single-cell RNA sequencing and 2 mass cytometry studies. In a comprehensive meta …

Tissue-resident memory CD8+ T cells possess unique transcriptional, epigenetic and functional adaptations to different tissue environments

JT Crowl, M Heeg, A Ferry, JJ Milner, KD Omilusik… - Nature …, 2022 - nature.com
Tissue-resident memory T cells (TRM cells) provide protective immunity, but the
contributions of specific tissue environments to TRM cell differentiation and homeostasis are …

The emerging role of resident memory T cells in protective immunity and inflammatory disease

CO Park, TS Kupper - Nature medicine, 2015 - nature.com
Over the past decade, it has become clear that there is an important subset of memory T
cells that resides in tissues—tissue-resident memory T (TRM) cells. There is an emerging …

The intricate role of CXCR4 in cancer

S Chatterjee, BB Azad, S Nimmagadda - Advances in cancer research, 2014 - Elsevier
Chemokines mediate numerous physiological and pathological processes related primarily
to cell homing and migration. The chemokine CXCL12, also known as stromal cell-derived …

The transcription factor GATA-3 controls cell fate and maintenance of type 2 innate lymphoid cells

T Hoyler, CSN Klose, A Souabni, A Turqueti-Neves… - Immunity, 2012 - cell.com
Innate lymphoid cells (ILCs) reside at mucosal surfaces and control immunity to intestinal
infections. Type 2 innate lymphoid cells (ILC2s) produce cytokines such as IL-5 and IL-13 …

Human MAIT cells are xenobiotic-resistant, tissue-targeted, CD161hi IL-17–secreting T cells

M Dusseaux, E Martin, N Serriari… - Blood, The Journal …, 2011 - ashpublications.org
Mucosal-associated invariant T (MAIT) cells are very abundant in humans and have
antimicrobial specificity, but their functions remain unclear. MAIT cells are CD161hiIL-18Rα+ …

mTOR regulates memory CD8 T-cell differentiation

K Araki, AP Turner, VO Shaffer, S Gangappa, SA Keller… - Nature, 2009 - nature.com
Memory CD8 T cells are a critical component of protective immunity, and inducing effective
memory T-cell responses is a major goal of vaccines against chronic infections and …

Central memory and effector memory T cell subsets: function, generation, and maintenance

F Sallusto, J Geginat, A Lanzavecchia - Annu. Rev. Immunol., 2004 - annualreviews.org
The memory T cell pool functions as a dynamic repository of antigen-experienced T
lymphocytes that accumulate over the lifetime of the individual. Recent studies indicate that …

Concise review: mesenchymal stem cells: their phenotype, differentiation capacity, immunological features, and potential for homing

G Chamberlain, J Fox, B Ashton, J Middleton - Stem cells, 2007 - academic.oup.com
MSCs are nonhematopoietic stromal cells that are capable of differentiating into, and
contribute to the regeneration of, mesenchymal tissues such as bone, cartilage, muscle …