The INO80 remodeller in transcription, replication and repair
The accessibility of eukaryotic genomes to the action of enzymes involved in transcription,
replication and repair is maintained despite the organization of DNA into nucleosomes. This …
replication and repair is maintained despite the organization of DNA into nucleosomes. This …
Ecdysone controlled cell and tissue deletion
T Xu, X Jiang, D Denton, S Kumar - Cell Death & Differentiation, 2020 - nature.com
The removal of superfluous and unwanted cells is a critical part of animal development. In
insects the steroid hormone ecdysone, the focus of this review, is an essential regulator of …
insects the steroid hormone ecdysone, the focus of this review, is an essential regulator of …
AtINO80 represses photomorphogenesis by modulating nucleosome density and H2A. Z incorporation in light-related genes
C Yang, L Yin, F Xie, M Ma, S Huang… - Proceedings of the …, 2020 - National Acad Sciences
Photomorphogenesis is a critical developmental process bridging light-regulated
transcriptional reprogramming with morphological changes in organisms. Strikingly, the …
transcriptional reprogramming with morphological changes in organisms. Strikingly, the …
Evolutionarily conserved roles for blood-brain barrier xenobiotic transporters in endogenous steroid partitioning and behavior
SJ Hindle, RN Munji, E Dolghih, G Gaskins, S Orng… - Cell reports, 2017 - cell.com
Central nervous system (CNS) chemical protection depends upon discrete control of small-
molecule access by the blood-brain barrier (BBB). Curiously, some drugs cause CNS side …
molecule access by the blood-brain barrier (BBB). Curiously, some drugs cause CNS side …
The chromatin‐remodeling factor At INO 80 plays crucial roles in genome stability maintenance and in plant development
INO 80 is a conserved chromatin‐remodeling factor in eukaryotes. While a previous study
reported that the Arabidopsis thaliana INO 80 (At INO 80) is required for somatic …
reported that the Arabidopsis thaliana INO 80 (At INO 80) is required for somatic …
INO80 requires a polycomb subunit to regulate the establishment of poised chromatin in murine spermatocytes
P Chakraborty, T Magnuson - Development, 2022 - journals.biologists.com
ABSTRACT INO80 is the catalytic subunit of the INO80-chromatin remodeling complex that
is involved in DNA replication, repair and transcription regulation. Ino80 deficiency in murine …
is involved in DNA replication, repair and transcription regulation. Ino80 deficiency in murine …
Hap2–Ino80-facilitated transcription promotes de novo establishment of CENP-A chromatin
PP Singh, M Shukla, SA White, M Lafos… - Genes & …, 2020 - genesdev.cshlp.org
Centromeres are maintained epigenetically by the presence of CENP-A, an evolutionarily
conserved histone H3 variant, which directs kinetochore assembly and hence centromere …
conserved histone H3 variant, which directs kinetochore assembly and hence centromere …
Chromatin remodeler mutations in human cancers: epigenetic implications
KA Skulte, L Phan, SJ Clark, PC Taberlay - Epigenomics, 2014 - Taylor & Francis
Chromatin remodeler complexes exhibit the ability to alter nucleosome composition and
positions, with seemingly divergent roles in the regulation of chromatin architecture and …
positions, with seemingly divergent roles in the regulation of chromatin architecture and …
INO80 represses osmostress induced gene expression by resetting promoter proximal nucleosomes
E Klopf, HA Schmidt, S Clauder-Münster… - Nucleic acids …, 2017 - academic.oup.com
The conserved INO80 chromatin remodeling complex is involved in regulation of DNA
damage repair, replication and transcription. It is commonly recruited to the transcription start …
damage repair, replication and transcription. It is commonly recruited to the transcription start …
A biological timer in the fat body comprising Blimp-1, βFtz-f1 and Shade regulates pupation timing in Drosophila melanogaster
K Akagi, M Sarhan, ARS Sultan, H Nishida… - …, 2016 - journals.biologists.com
During the development of multicellular organisms, many events occur with precise timing.
In Drosophila melanogaster, pupation occurs about 12 h after puparium formation and its …
In Drosophila melanogaster, pupation occurs about 12 h after puparium formation and its …