It is well acknowledged that allogeneic hematopoietic stem cell transplantation (allo-HSCT)
is an effective treatment for numerous malignant blood diseases, which has also been …

Bone marrow mesenchymal stem cells (BMSCs) characterized multi-directional
differentiation, low immunogenicity and high portability, serve as ideal “seed cells” in …

Rationale: The effectiveness of stem cell based-therapy for bone regeneration has been
demonstrated; yet, clinical application of autologous stem cells is still limited by invasive …

Solid abdominal organ transplantation is fraught with variable rates of rejection and graft
versus host disease (GVHD). We sought to determine the safety and efficacy of an advanced …

Objective To determine the efficacy of CXCL5 administration in lupus‐prone MRL/lpr (Fas
lpr) mice and elucidate its working mechanisms. Methods CXCL5 expression in blood …

Human placenta-derived mesenchymal stromal cells (hPMSCs) are promising candidates
for the treatment of graft-versus-host disease (GVHD), which is associated with high IL-1β …

Objective: Steroid-resistant acute graft-versus-host disease (srAGVHD) is the most important
cause of morbidity and mortality after allogeneic stem cell transplantation. There are several …

Pyroptosis represents one type of Programmed Cell Death (PCD). It is a form of inflammatory
cell death that is canonically defined by caspase-1 cleavage and Gasdermin-mediated …

Despite therapeutic advancements, GVHD is a major complication of HSCT. In current
models of GVHD, tissue injury induced by cytotoxic conditioning regimens, along with …

Mesenchymal stem cells (MSCs) are a subset of multifunctional stem cells with self‐renewal
and multidirectional differentiation properties that play a pivotal role in tumor progression …