Cancer is one of the most common causes of death globally. Despite extensive research
and considerable advances in cancer therapy, the fundamentals of the disease remain …

To understand the emergence of human higher cognition, we must understand its biological
substrate—the cerebral cortex, which considers itself the crowning achievement of evolution …

Searches for the genetic underpinnings of uniquely human traits have focused on human-
specific divergence in conserved genomic regions, which reflects adaptive modifications of …

The hippocampus is an important part of the limbic system in the human brain that has
essential roles in spatial navigation and the consolidation of information from short-term …

A suite of recent studies has reported positive genetic correlations between autism risk and
measures of mental ability. These findings indicate that alleles for autism overlap broadly …

Advances in genome sequencing technologies have created new opportunities for
comparative primate genomics. Genome assemblies have been published for various …

Duplications are the primary force by which new gene functions arise and provide a
substrate for large-scale structural variation. Analysis of thousands of genomes shows that …

Watson‐Crick base‐pair changes, or single‐nucleotide variants (SNV), have long been
known as a source of mutations. However, the extent to which DNA structural variation …

Given the unprecedented tools that are now available for rapidly comparing genomes, the
identification and study of genetic and genomic changes that are unique to our species have …

Throughout the past decade, studying ancient genomes has provided unique insights into
human prehistory, and differences between modern humans and other branches like …