Understanding how chromatin is organized within the nucleus and how this 3D architecture
influences gene regulation, cell fate decisions and evolution are major questions in cell …

Most land plants are now known to be ancient polyploids that have rediploidized.
Diploidization involves many changes in genome organization that ultimately restore …

The precise pattern and timing of speciation events that gave rise to all living placental
mammals remain controversial. We provide a comprehensive phylogenetic analysis of …

Decrypting the rearrangements that drive mammalian chromosome evolution is critical to
understanding the molecular bases of speciation, adaptation, and disease susceptibility …

Recent outbreaks of food-borne diseases highlight the need for reducing bacterial
pathogens in foods of animal origin. Animal enteric pathogens are a direct source for food …

The Genome 10K Project was established in 2009 by a consortium of biologists and
genome scientists determined to facilitate the sequencing and analysis of the complete …

MicroRNAs (miRNAs) are small noncoding regulatory RNAs that reduce stability and/or
translation of fully or partially sequence-complementary target mRNAs. In order to identify …

To understand the biology and evolution of ruminants, the cattle genome was sequenced to
about sevenfold coverage. The cattle genome contains a minimum of 22,000 genes, with a …

Numerous studies of ecological genetics have found that alleles contributing to local
adaptation sometimes cluster together, forming “genomic islands of divergence.” Divergence …

Background Microbial inhabitants of soils are important to ecosystem and planetary
functions, yet there are large gaps in our knowledge of their diversity and ecology. The …