Iron is an essential element required by cells and has been described as a key player in
ferroptosis. Ferritin operates as a fundamental iron storage protein in cells forming …

Life on earth is dependent on the catalytic activity of a number of different metal ions in their
polypeptide scaffold. Of these metals iron is widely used for catalysis of many reactions by …

Ferritin is a protein that stores and releases iron to prevent diseases associated with iron
dysregulation in plants, animals, and bacteria. The conversion between iron-loaded holo …

Ferritin is a vital protein complex responsible for storing iron in almost all living organisms. It
plays a crucial role in various metabolic pathways, inflammation processes, stress response …

Ferritins, the main intracellular iron storage proteins, have been studied for over 60 years,
mainly focusing on the mammalian ones. This allowed the elucidation of the structure of …

Protein cages are a common architectural motif used by living organisms to
compartmentalize and control biochemical reactions. While engineered protein cages have …

Recent advances in biomedicine largely rely on the development in nanoengineering. As
the access to unique properties in biomaterials is not readily available from traditional …

Background Until recently thought to be of little significance unless occurring during
pregnancy, Toxoplasma gondii infection of human hosts is now known to play a larger role …

Ferritin molecular cages are marvelous 24-mer supramolecular architectures that enable
massive iron storage (> 2000 iron atoms) within their inner cavity. This cavity is connected to …

Tumor-specific apoptosis-inducing ligands have attracted considerable attention in cancer
therapy. But, the evasion of apoptosis by tumors can cause acquired resistance to the …