Primary ciliary dyskinesia is a genetically and clinically heterogeneous syndrome. Impaired
function of motile cilia causes failure of mucociliary clearance. Patients typically present with …

Pediatric non-cystic fibrosis (CF) bronchiectasis is characterized by endobronchial
suppuration, airway neutrophilic inflammation and poor mucus clearance and is associated …

Rationale: Primary ciliary dyskinesia (PCD) is an inherited disorder characterized by
heterogeneous airway disease. Traditional lung function techniques (eg, spirometry) may …

Rationale: Preterm birth is associated with low lung function in childhood, but little is known
about the lung microstructure in childhood. Objectives: We assessed the differential …

Rationale: Primary ciliary dyskinesia (PCD) and cystic fibrosis (CF) are characterized by
inherited impaired mucociliary clearance leading to chronic progressive lung disease as …

Primary ciliary dyskinesia (PCD) is a rare, genetically heterogeneous, motile ciliopathy,
characterized by neonatal respiratory distress, recurrent upper and lower respiratory tract …

Background: Primary ciliary dyskinesia (PCD) is characterized by impaired mucociliary
clearance that results in accumulation of mucus and bacteria in the airways. Lower …

Objectives Disease-specific, well-defined and validated clinical outcome measures are
essential in designing research studies. Poorly defined outcome measures hamper pooling …

RATIONALE Primary ciliary dyskinesia (PCD) is an inherited disorder characterized by
heterogeneous airway disease. Traditional lung function techniques (eg spirometry) may …

Lung function testing and lung imaging are commonly used techniques to monitor
respiratory diseases, such as cystic fibrosis (CF). The nitrogen (N 2) multiple-breath washout …