Fluorochemicals from fluorspar via a phosphate-enabled mechanochemical process that bypasses HF

C Patel, E André-Joyaux, JA Leitch… - Science, 2023 - science.org
All fluorochemicals—including elemental fluorine and nucleophilic, electrophilic, and radical
fluorinating reagents—are prepared from hydrogen fluoride (HF). This highly toxic and …

Mechanosynthesis of sulfonamides via a telescopic, environmentally friendly, and cost-effective process

F Cuccu, A Porcheddu - Green Chemistry, 2024 - pubs.rsc.org
Herein, we demonstrate a solvent-free mechanochemical approach involving a one-pot-
double-step procedure mediated by solid sodium hypochlorite (NaOCl· 5H2O) for the …

Manganese-promoted reductive cross-coupling of disulfides with dialkyl carbonates

CP Zhang, TZ Wang, YF Liang - Chemical Communications, 2023 - pubs.rsc.org
Manganese is a cheap and environmentally friendly metal on Earth. Herein, we report a
manganese-promoted reductive cross-coupling using easily available and odorless …

Asymmetric synthesis of sulfoximines, sulfonimidoyl fluorides and sulfonimidamides enabled by an enantiopure bifunctional S (VI) reagent

S Teng, ZP Shultz, C Shan, L Wojtas, JM Lopchuk - Nature Chemistry, 2024 - nature.com
An increased interest to expand three-dimensional chemical space for the design of new
materials and medicines has created a demand for isosteric replacement groups of …

Mechanochemical Deoxyfluorination of Carboxylic Acids to Acyl Fluorides and Successive Mechanochemical Amide Bond Formation

Z Zhao, S Ikawa, S Mori, Y Sumii… - ACS Sustainable …, 2024 - ACS Publications
Diverse methods have been reported for the synthesis of acyl fluorides; however, an
environmentally benign synthesis method for acyl fluorides remains underdeveloped. In this …

Mechanical‐Force‐Induced Non‐spontaneous Dehalogenative Deuteration of Aromatic Iodides Enabled by Using Piezoelectric Materials as a Redox Catalyst

R Qu, S Wan, X Zhang, X Wang, L Xue… - Angewandte Chemie …, 2024 - Wiley Online Library
The development of green and efficient deuteration methods is of great significance for
various fields such as organic synthesis, analytical chemistry, and medicinal chemistry …

Mechanochemical aerobic oxidative Heck coupling by polymer-assisted grinding: cyclodextrin additive facilitating regioselectivity control

K Xiang, H Shou, C Hu, W Su, J Yu - Green Chemistry, 2024 - pubs.rsc.org
The oxidative Heck reaction is a well-known organic transformation. However, previous
reactions have been limited by the need for sophisticated directing or auxiliary groups …

A General Electrochemical Synthesis of Sulfonimidoyl Fluorides, Azides, and Acetates

YM Jiang, YY Lin, L Zhu, Y Yu, Y Li, Y Lin… - CCS …, 2024 - chinesechemsoc.org
Sulfonimidoyl fluorides, the aza-bioisostere of sulfonyl fluorides, are emerging as a
promising linkage agent in the sulfur (VI) fluoride exchange reaction (SuFEx). However …

Green and Efficient Protocols for the Synthesis of Sulfonyl Fluorides Using Potassium Fluoride as the Sole Fluorine Source

S Yamahara, MSH Salem, T Kawai… - ACS Sustainable …, 2024 - ACS Publications
Sulfonyl fluorides are highly versatile organic compounds with diverse applications in click
chemistry, biochemistry, and materials science. However, traditional synthetic approaches …

Formation, functionalization and interconversion of sulfur containing functional groups in mechanochemical conditions

K Bugaj, P Pokora-Sobczak, G Mielniczak… - … , Sulfur, and Silicon …, 2023 - Taylor & Francis
In the recent three decades, a steadily growing interest in the use of ball milling in organic
synthesis has developed. The purpose of this mini-review is to briefly present protocols …