In recent years, exceptional technological advances have enabled the identification and
interrogation of rare circulating tumour cells (CTCs) from blood samples of patients, leading …

Gastric cancer (GC) is one of the most common tumors worldwide and the leading cause of
tumor-related mortality. Endoscopy and serological tumor marker testing are currently the …

Despite the high long-term survival in localized prostate cancer, metastatic prostate cancer
remains largely incurable even after intensive multimodal therapy. The lethality of advanced …

Purpose Both temozolomide (TMZ) and poly (ADP-ribose) polymerase (PARP) inhibitors are
active in small-cell lung cancer (SCLC). This phase II, randomized, double-blind study …

Technological advancements in research on circulating biomarkers from patient derived
blood have enabled a less invasive means of diagnosing non-hematologic cancers …

Extracellular vesicles (EVs) are small lipid membrane vesicles that are secreted from almost
all kinds of cells into the extracellular space. EVs are widely accepted to be involved in …

Abstract Background Extracellular microRNAs (miRNAs) embedded in circulating exosomes
may serves as prognostic biomarkers in cancer. Objective To identify and evaluate plasma …

The ability to study nonhematologic cancers through noninvasive sampling of blood is one
of the most exciting and rapidly advancing fields in cancer diagnostics. This has been driven …

Background A major limitation of circulating tumor DNA (ctDNA) for somatic mutation
detection has been the low level of ctDNA found in a subset of cancer patients. We …

Background The use of biomarkers for prostate cancer screening, diagnosis and prognosis
has the potential to improve the clinical management of the patients. Owing to inherent …