Management of treatment-resistant depression: challenges and strategies

D Voineskos, ZJ Daskalakis… - … disease and treatment, 2020 - Taylor & Francis
Abstract Treatment-resistant depression (TRD) is a subset of Major Depressive Disorder
which does not respond to traditional and first-line therapeutic options. There are several …

Canadian Network for Mood and Anxiety Treatments (CANMAT) 2016 clinical guidelines for the management of adults with major depressive disorder: section 4 …

RV Milev, P Giacobbe, SH Kennedy… - The Canadian …, 2016 - journals.sagepub.com
Background: The Canadian Network for Mood and Anxiety Treatments (CANMAT)
conducted a revision of the 2009 guidelines by updating the evidence and …

Stanford neuromodulation therapy (SNT): a double-blind randomized controlled trial

EJ Cole, AL Phillips, BS Bentzley… - American Journal of …, 2022 - Am Psychiatric Assoc
Objective: Depression is the leading cause of disability worldwide, and half of patients with
depression have treatment-resistant depression. Intermittent theta-burst stimulation (iTBS) is …

Stanford accelerated intelligent neuromodulation therapy for treatment-resistant depression

EJ Cole, KH Stimpson, BS Bentzley… - American Journal of …, 2020 - Am Psychiatric Assoc
Objective: New antidepressant treatments are needed that are effective, rapid acting, safe,
and tolerable. Intermittent theta-burst stimulation (iTBS) is a noninvasive brain stimulation …

Effectiveness of theta burst versus high-frequency repetitive transcranial magnetic stimulation in patients with depression (THREE-D): a randomised non-inferiority trial

DM Blumberger, F Vila-Rodriguez, KE Thorpe, K Feffer… - The Lancet, 2018 - thelancet.com
Background Treatment-resistant major depressive disorder is common; repetitive
transcranial magnetic stimulation (rTMS) by use of high-frequency (10 Hz) left-side …

Effectiveness of standard sequential bilateral repetitive transcranial magnetic stimulation vs bilateral theta burst stimulation in older adults with depression: the FOUR …

DM Blumberger, BH Mulsant, KE Thorpe… - JAMA …, 2022 - jamanetwork.com
Importance Treatment-resistant depression (TRD) is common in older adults. Bilateral
repetitive transcranial magnetic stimulation (rTMS) of the dorsolateral prefrontal cortex for 48 …

Comparative efficacy and acceptability of non-surgical brain stimulation for the acute treatment of major depressive episodes in adults: systematic review and network …

J Mutz, V Vipulananthan, B Carter, R Hurlemann… - bmj, 2019 - bmj.com
Objective To estimate the comparative clinical efficacy and acceptability of non-surgical
brain stimulation for the acute treatment of major depressive episodes in adults. Design …

Repetitive transcranial magnetic stimulation for the acute treatment of major depressive episodes: a systematic review with network meta-analysis

AR Brunoni, A Chaimani, AH Moffa, LB Razza… - JAMA …, 2017 - jamanetwork.com
Importance Although several strategies of repetitive transcranial magnetic stimulation (rTMS)
have been investigated as treatment of major depressive disorder (MDD), their comparative …

Ten years of theta burst stimulation in humans: established knowledge, unknowns and prospects

A Suppa, YZ Huang, K Funke, MC Ridding, B Cheeran… - Brain stimulation, 2016 - Elsevier
Background/objectives Over the last ten years, an increasing number of authors have used
the theta burst stimulation (TBS) protocol to investigate long-term potentiation (LTP) and …

Magnitude of the placebo response across treatment modalities used for treatment-resistant depression in adults: a systematic review and meta-analysis

BDM Jones, LB Razza, CR Weissman, J Karbi… - JAMA network …, 2021 - jamanetwork.com
Importance The placebo effect in depression clinical trials is a substantial factor associated
with failure to establish efficacy of novel and repurposed treatments. However, the …