Atherosclerosis is a significant cardiovascular burden and a leading cause of death
worldwide, recognized as a chronic sterile inflammatory disease. Pyroptosis is a novel …

Extraosseous calcification is a pathologic mineralization process occurring in soft connective
tissues (eg, skin, vessels, tendons, and cartilage). It can take place on a genetic basis or as …

Inflammatory cytokine–induced activation of nuclear factor κB (NF-κB) signaling plays a
critical role in the pathogenesis of osteoarthritis (OA). We identified PILA as a long …

Background Breast cancer (BC) is by far the most common malignancy among women.
Epigenetic modulators, microRNAs in particular, may set stages for BC development and its …

The repair of damaged cartilage still remains a great challenge in clinic. It is demonstrated
that bone marrow stromal cells (BMSCs)‐chondrocytes communication is of great …

Aim Colorectal carcinoma (CRC) is one of the most prevalent cancers throughout the world.
Circulating serum-derived microRNAs (miRNAs, miRs) can be used as non-invasive …

Background Mesenchymal stem cell (MSC)-based cartilage tissue regeneration is a
treatment with great potential. How to enhance the MSC chondrogenic differentiation is a …

During the last decade, osteoarthritis (OA) has become one of the most prevalent
musculoskeletal diseases worldwide. OA is characterized by progressive loss of articular …

Osteoarthritis (OA) is a common chronic degenerative joint disease in clinical practice with a
high prevalence, especially in the elderly. Traditional Chinese Medicine (TCM) believes that …

Background Gastric cancer (GC) is a major health issue in the Western world. Current
clinical imperatives for this disease include the identification of more effective biomarkers to …