The majority of coronary atherothrombotic events presenting as myocardial infarction (MI)
occur as a result of plaque rupture or erosion. Understanding the evolution from a stable …

Fluorescence lifetime imaging (FLIm) is an optical spectroscopic imaging technique capable
of real‐time assessments of tissue properties in clinical settings. Label‐free FLIm is sensitive …

Fluorescent nanosensors hold the potential to revolutionize life sciences and medicine.
However, their adaptation and translation into the in vivo environment is fundamentally …

Endothelial cell (EC) glycocalyx (GCX) loss permits blood circulating particle infiltration of
the vessel walls and leads to vascular dysfunction, atherosclerosis, and serious downstream …

Tumor-free surgical margins are critical in breast-conserving surgery. In up to 38% of the
cases, however, patients undergo a second surgery since malignant cells are found at the …

Miniaturised high-resolution imaging devices are valuable for guiding minimally invasive
procedures such as vascular stent placements. Here, we present all-optical rotational B …

Autofluorescence spectroscopy has emerged in recent years as a powerful tool to report
label-free contrast between normal and diseased tissues, both in vivo and ex vivo. We report …

Background: Autofluorescence lifetime (AFL) imaging, a robust technique that enables label-
free molecular investigation of biological tissues, is being introduced into the field of …

Background This study evaluated whether fluorescence lifetime imaging (FLIm), coupled
with standard diagnostic workups, could enhance primary lesion detection in patients with …

Comprehensive imaging of both the structural and biochemical characteristics of
atherosclerotic plaque is essential for the diagnosis and study of coronary artery disease …