Flavonoids as anticancer agents

DM Kopustinskiene, V Jakstas, A Savickas… - Nutrients, 2020 - mdpi.com
Flavonoids are polyphenolic compounds subdivided into 6 groups: isoflavonoids,
flavanones, flavanols, flavonols, flavones and anthocyanidins found in a variety of plants …

The role of catechins in cellular responses to oxidative stress

J Bernatoniene, DM Kopustinskiene - Molecules, 2018 - mdpi.com
Catechins are polyphenolic compounds—flavanols of the flavonoid family found in a variety
of plants. Green tea, wine and cocoa-based products are the main dietary sources of these …

[HTML][HTML] Hydrogen peroxide sensing, signaling and regulation of transcription factors

HS Marinho, C Real, L Cyrne, H Soares, F Antunes - Redox biology, 2014 - Elsevier
The regulatory mechanisms by which hydrogen peroxide (H 2 O 2) modulates the activity of
transcription factors in bacteria (OxyR and PerR), lower eukaryotes (Yap1, Maf1, Hsf1 and …

Peroxisomal hydrogen peroxide metabolism and signaling in health and disease

C Lismont, I Revenco, M Fransen - International Journal of Molecular …, 2019 - mdpi.com
Hydrogen peroxide (H2O2), a non-radical reactive oxygen species generated during many
(patho) physiological conditions, is currently universally recognized as an important …

Recent advances in natural polyphenol research

I Dini, L Grumetto - Molecules, 2022 - mdpi.com
Polyphenols are secondary metabolites produced by plants, which contribute to the plant's
defense against abiotic stress conditions (eg, UV radiation and precipitation), the aggression …

Role of hydrogen peroxide in NF-κB activation: from inducer to modulator

V Oliveira-Marques, HS Marinho, L Cyrne… - Antioxidants & redox …, 2009 - liebertpub.com
Abstract Hydrogen peroxide (H2O2) has been implicated in the regulation of the
transcription factor NF-κB, a key regulator of the inflammatory process and adaptive …

Ginsenoside Rg1 protects against hydrogen peroxide-induced cell death in PC12 cells via inhibiting NF-κB activation

Q Liu, JP Kou, BY Yu - Neurochemistry international, 2011 - Elsevier
Oxidative stress is a major cause in neurodegenerative diseases including Alzheimer's
disease (AD), Parkinson's disease (PD), and cerebral ischemia. Ginsenoside Rg1, a natural …

Nuclear factor kappa B signaling complexes in acute inflammation

S Rius-Pérez, S Pérez, P Martí-Andrés… - Antioxidants & redox …, 2020 - liebertpub.com
Significance: Nuclear factor kappa B (NF-κB) is a master regulator of the inflammatory
response and represents a key regulatory node in the complex inflammatory signaling …

ATP Modulates Acute Inflammation In Vivo through Dual Oxidase 1–Derived H2O2 Production and NF-κB Activation

S De Oliveira, A López-Muñoz, S Candel… - The Journal of …, 2014 - journals.aai.org
Abstract Dual oxidase 1 (Duox1) is the NADPH oxidase responsible for the H 2 O 2 gradient
formed in tissues after injury to trigger the early recruitment of leukocytes. Little is known …

[HTML][HTML] Moringa oleifera leaves ethanolic extract ameliorates high fat diet-induced obesity in rats

AM El-Shehawi, M Alkafafy, S El-Shazly… - Journal of King Saud …, 2021 - Elsevier
Obesity is one of the major health problems worldwide. This study aimed to evaluate anti-
obesity potential of Moringa oleifera leaves ethanolic extract (MOE) in rats. Fifty male Wistar …