The Legionella pneumophila Dot/Icm type IV secretion system and its effectors

DC Lockwood, H Amin, TRD Costa… - …, 2022 - microbiologyresearch.org
To prevail in the interaction with eukaryotic hosts, many bacterial pathogens use protein
secretion systems to release virulence factors at the host–pathogen interface and/or deliver …

[HTML][HTML] Comparative analysis of T4SS Molecular architectures

M Zehra, J Heo, JM Chung, CL Durie - Journal of Microbiology and …, 2023 - ncbi.nlm.nih.gov
The recently published high-resolution R388 T4SS structure provides exciting new details
about the complete complex of T4SS, including the components making up the stalk and …

Membrane association and polar localization of the Legionella pneumophila T4SS DotO ATPase mediated by two nonredundant receptors

S Vijayrajratnam, S Milek, S Maggi, K Ashen… - Proceedings of the …, 2024 - pnas.org
The Legionella pneumophila Dot/Icm type IVB secretion system (T4BSS) is a large,
multisubunit complex that exports a vast array of substrates into eukaryotic host cells. DotO …

Migration of Acanthamoeba through Legionella biofilms is regulated by the bacterial Lqs‐LvbR network, effector proteins and the flagellum

R Hochstrasser, S Michaelis… - Environmental …, 2022 - Wiley Online Library
The environmental bacterium Legionella pneumophila causes the pneumonia Legionnaires'
disease. The opportunistic pathogen forms biofilms and employs the Icm/Dot type IV …

Functional Analysis of the $\textit {Legionella pneumophila} $ Nitric Oxide Regulatory Network and its Link to Quorum Sensing

S Michaelis - 2024 - zora.uzh.ch
Legionella pneumophila is a ubiquitous Gram-negative bacterium and the causative agent
of Legionnaires' disease and Pontiac fever. The facultative intracellular bacterium colonizes …