Global climate changes cause extreme temperatures and a significant reduction in crop
production, leading to food insecurity worldwide. Temperature extremes (including both heat …

Melatonin is an ancient molecule that can be traced back to the origin of life. Melatonin's
initial function was likely that as a free radical scavenger. Melatonin presumably evolved in …

Melatonin is a multi-functional molecule that is ubiquitous in all living organisms. Melatonin
performs essential roles in plant stress tolerance; its application can reduce the harmful …

Melatonin is a ubiquitous indolamine, largely investigated for its key role in the regulation of
several physiological processes in both animals and plants. In the last century, it was …

Melatonin is a multifunctional biomolecule found in both animals and plants. In this review,
the biosynthesis, levels, signaling, and possible roles of melatonin and its metabolites in …

L-5-hydroxytryptophan (5-HTP) is both a drug and a natural component of some dietary
supplements. 5-HTP is produced from tryptophan by tryptophan hydroxylase (TPH), which is …

It was a surprising discovery when mitochondria, as the power houses of cells, were also
found to synthesize the potent mitochondrial targeted antioxidant, melatonin. The melatonin …

Plant melatonin research is a rapidly developing field. A variety of isoforms of melatonin's
biosynthetic enzymes are present in different plants. Due to the different origins, they exhibit …

Increasing food demand by the growing human population and declining crop productivity
due to climate change affect global food security. To meet the challenges, developing …

Cadmium (Cd) is one of the most injurious heavy metals, affecting plant growth and
development. Melatonin (N-acetyl-5-methoxytryptamine) was discovered in plants in 1995 …