M1 and M2 macrophage polarization and potentially therapeutic naturally occurring compounds
Macrophages, as crucial cellular components of innate immunity, are characterized by
possessing high plasticity and an abnormal ability to differentiate in response to numerous …
possessing high plasticity and an abnormal ability to differentiate in response to numerous …
The role of metabolic remodeling in macrophage polarization and its effect on skeletal muscle regeneration
F De Santa, L Vitiello, A Torcinaro… - Antioxidants & redox …, 2019 - liebertpub.com
Significance: Macrophages are crucial for tissue homeostasis. Based on their activation,
they might display classical/M1 or alternative/M2 phenotypes. M1 macrophages produce pro …
they might display classical/M1 or alternative/M2 phenotypes. M1 macrophages produce pro …
The role of Omega-3 polyunsaturated fatty acids and their lipid mediators on skeletal muscle regeneration: a narrative review
Skeletal muscle is the largest tissue in the human body, comprising approximately 40% of
body mass. After damage or injury, a healthy skeletal muscle is often fully regenerated; …
body mass. After damage or injury, a healthy skeletal muscle is often fully regenerated; …
[HTML][HTML] A biomaterial-based therapy for lower limb ischemia using Sr/Si bioactive hydrogel that inhibits skeletal muscle necrosis and enhances angiogenesis
Y Yuan, Z Zhang, F Mo, C Yang, Y Jiao, E Wang… - Bioactive Materials, 2023 - Elsevier
Muscle necrosis and angiogenesis are two major challenges in the treatment of lower-limb
ischemic diseases. In this study, a triple-functional Sr/Si-containing bioceramic/alginate …
ischemic diseases. In this study, a triple-functional Sr/Si-containing bioceramic/alginate …
Inhibition of sphingolipid de novo synthesis counteracts muscular dystrophy
Duchenne muscular dystrophy (DMD), the most common muscular dystrophy, is a severe
muscle disorder, causing muscle weakness, loss of independence, and premature death …
muscle disorder, causing muscle weakness, loss of independence, and premature death …
Impaired skeletal muscle regeneration in diabetes: From cellular and molecular mechanisms to novel treatments
E Espino-Gonzalez, E Dalbram, R Mounier, J Gondin… - Cell Metabolism, 2024 - cell.com
Diabetes represents a major public health concern with a considerable impact on human life
and healthcare expenditures. It is now well established that diabetes is characterized by a …
and healthcare expenditures. It is now well established that diabetes is characterized by a …
Skeletal muscle metabolism in duchenne and becker muscular dystrophy—Implications for therapies
A Heydemann - Nutrients, 2018 - mdpi.com
The interactions between nutrition and metabolism and skeletal muscle have long been
known. Muscle is the major metabolic organ—it consumes more calories than other organs …
known. Muscle is the major metabolic organ—it consumes more calories than other organs …
Eicosapentaenoic acid enhances the effects of mesenchymal stromal cell therapy in experimental allergic asthma
SC Abreu, M Lopes-Pacheco, AL Da Silva… - Frontiers in …, 2018 - frontiersin.org
Asthma is characterized by chronic lung inflammation and airway hyperresponsiveness.
Despite recent advances in the understanding of its pathophysiology, asthma remains a …
Despite recent advances in the understanding of its pathophysiology, asthma remains a …
Long‐term administration of eicosapentaenoic acid improves post–myocardial infarction cardiac remodeling in mice by regulating macrophage polarization
M Takamura, K Kurokawa, H Ootsuji… - Journal of the …, 2017 - Am Heart Assoc
Background Consumption of n‐3 fatty acids reduces the incidence of cardiovascular
mortality in populations that consume diets rich in fish oil. Eicosapentaenoic acid (EPA) is an …
mortality in populations that consume diets rich in fish oil. Eicosapentaenoic acid (EPA) is an …
Polarized macrophages regulate fibro/adipogenic progenitor (FAP) adipogenesis through exosomes
Background Macrophage polarization has been observed in the process of muscle injuries
including rotator cuff (RC) muscle atrophy and fatty infiltration after large tendon tears. In our …
including rotator cuff (RC) muscle atrophy and fatty infiltration after large tendon tears. In our …