Neglected, yet significant role of FOXP1 in T-cell quiescence, differentiation and exhaustion
Y Kaminskiy, V Kuznetsova, A Kudriaeva… - Frontiers in …, 2022 - frontiersin.org
FOXP1 is ubiquitously expressed in the human body and is implicated in both physiological
and pathological processes including cancer. However, despite its importance the role of …
and pathological processes including cancer. However, despite its importance the role of …
Multiple functions and regulatory network of miR-150 in B lymphocyte-related diseases
MicroRNAs (miRNAs) play vital roles in the post-transcriptional regulation of gene
expression. Previous studies have shown that miR-150 is a crucial regulator of B cell …
expression. Previous studies have shown that miR-150 is a crucial regulator of B cell …
PD-1/PD-L1 immune checkpoint and p53 loss facilitate tumor progression in activated B-cell diffuse large B-cell lymphomas
M Pascual, M Mena-Varas, EF Robles… - Blood, The Journal …, 2019 - ashpublications.org
Refractory or relapsed diffuse large B-cell lymphoma (DLBCL) often associates with the
activated B-cell-like (ABC) subtype and genetic alterations that drive constitutive NF-κB …
activated B-cell-like (ABC) subtype and genetic alterations that drive constitutive NF-κB …
FOXP1 drives osteosarcoma development by repressing P21 and RB transcription downstream of P53
Osteosarcoma has a poor prognosis, and the poor understanding of the genetic drivers of
osteosarcoma hinders further improvement in therapeutic approaches. Transcription factor …
osteosarcoma hinders further improvement in therapeutic approaches. Transcription factor …
MicroRNA miR-34a downregulates FOXP1 during DNA damage response to limit BCR signalling in chronic lymphocytic leukaemia B cells
The variable clinical course in chronic lymphocytic leukaemia (CLL) largely depends on p53
functionality and B-cell receptor (BCR) signalling propensity; however, it is unclear if there is …
functionality and B-cell receptor (BCR) signalling propensity; however, it is unclear if there is …
Severe speech impairment is a distinguishing feature of FOXP1‐related disorder
Aim To delineate the speech and language phenotype of a cohort of individuals with FOXP1‐
related disorder. Method We administered a standardized test battery to examine speech …
related disorder. Method We administered a standardized test battery to examine speech …
miR-150 downregulation contributes to the high-grade transformation of follicular lymphoma by upregulating FOXP1 levels
Follicular lymphoma (FL) is a common indolent B-cell malignancy with a variable clinical
course. An unfavorable event in its course is histological transformation to a high-grade …
course. An unfavorable event in its course is histological transformation to a high-grade …
MiR-378a-3p is critical for Burkitt lymphoma cell growth
F Niu, A Dzikiewicz-Krawczyk, J Koerts, D de Jong… - Cancers, 2020 - mdpi.com
Simple Summary MicroRNAs (miRNAs) are small RNAs that regulate expression of specific
target genes. We observed elevated levels of miR-378a-3p in Burkitt lymphoma (BL) and …
target genes. We observed elevated levels of miR-378a-3p in Burkitt lymphoma (BL) and …
Identification of a forkhead box protein transcriptional network induced in human neutrophils in response to inflammatory stimuli
A Ismailova, R Salehi-Tabar, V Dimitrov… - Frontiers in …, 2023 - frontiersin.org
Introduction Neutrophils represent the largest proportion of circulating leukocytes and, in
response to inflammatory stimuli, are rapidly recruited to sites of infection where they …
response to inflammatory stimuli, are rapidly recruited to sites of infection where they …
miR-34a-FOXP1 Loop in Ovarian Cancer
E Dirimtekin, M Mortoglou, C Alavanda… - ACS …, 2023 - ACS Publications
Ovarian cancer (OC) is the main cause of gynecological cancer mortality in most developed
countries. microRNA (miR) expression dysregulation has been highlighted in human …
countries. microRNA (miR) expression dysregulation has been highlighted in human …