2, 5-Diketopiperazines: synthesis, reactions, medicinal chemistry, and bioactive natural products

AD Borthwick - Chemical reviews, 2012 - ACS Publications
2, 5-Diketopiperazines (2, 5-DKPs) are cyclodipeptides obtained by the condensation of two
α-amino acids. They not only abound in nature but are often produced as degradation …

Cyclic dipeptides: The biological and structural landscape with special focus on the anti-cancer proline-based scaffold

J Bojarska, A Mieczkowski, ZM Ziora, M Skwarczynski… - Biomolecules, 2021 - mdpi.com
Cyclic dipeptides, also know as diketopiperazines (DKP), the simplest cyclic forms of
peptides widespread in nature, are unsurpassed in their structural and bio-functional …

Diketopiperazines: biological activity and synthesis

MB Martins, I Carvalho - Tetrahedron, 2007 - Elsevier
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Purification of a new antifungal compound produced by Lactobacillus plantarum AF1 isolated from kimchi

EJ Yang, HC Chang - International journal of food microbiology, 2010 - Elsevier
The aim of this study was to purify and to identify an antifungal compound of Lactobacillus
plantarum AF1, which was isolated from kimchi, and to determine if Lb. plantarum AF1 can …

Antimicrobial and biofilm inhibiting diketopiperazines

MP de Carvalho, WR Abraham - Current medicinal chemistry, 2012 - ingentaconnect.com
Diketopiperazines are the smallest cyclic peptides known. 90% of Gram-negative bacteria
produce diketopiperazines and they have also been isolated from Gram-positive bacteria …

The nonribosomal synthesis of diketopiperazines in tRNA-dependent cyclodipeptide synthase pathways

P Belin, M Moutiez, S Lautru, J Seguin… - Natural product …, 2012 - pubs.rsc.org
Covering: up to 2012 We review here work on the biosynthesis of diketopiperazines (DKPs),
a large class of natural products with noteworthy biological activities, focusing on the …

Cyclic dipeptides: Biological activities and self‐assembled materials

K Zhao, R Xing, X Yan - Peptide Science, 2021 - Wiley Online Library
Cyclic dipeptides (CDPs) are the smallest cyclic peptides containing 2, 5‐diketopiperazine
rings. CDPs have advantages of structures and properties, including excellent hydrogen …

Antibacterial substances of low molecular weight isolated from the blowfly, Lucilia sericata

L Huberman, N Gollop… - Medical and …, 2007 - Wiley Online Library
Low molecular weight compounds were isolated by high‐performance liquid
chromatography from the maggot or haemolymph extracts of Lucilia sericata …

Identification of Antifungal Compounds Produced by Lactobacillus casei AST18

H Li, L Liu, S Zhang, W Cui, J Lv - Current microbiology, 2012 - Springer
Lactobacillus casei AST18 was screened as an antifungal lactic acid bacteria which we
have reported before. In this research, the antifungal properties of cell-free culture filtrate …

Antifouling diketopiperazines produced by a deep-sea bacterium, Streptomyces fungicidicus

X Li, S Dobretsov, Y Xu, X Xiao, OS Hung, P Qian - Biofouling, 2006 - Taylor & Francis
Modern antifouling coatings use heavy metals and toxic organic molecules to prevent
biofouling, the undesirable growth of marine organisms on man-made substrata. In an …