Biomolecular condensates are membraneless organelle-like structures that can concentrate
molecules and often form through liquid-liquid phase separation. Biomolecular condensate …

Compared with traditional therapies, targeted therapy has merits in selectivity, efficacy, and
tolerability. Small molecule inhibitors are one of the primary targeted therapies for cancer …

Compartmentalization is crucial for the functioning of cells. Membranes enclose and protect
the cell, regulate the transport of molecules entering and exiting the cell, and organize …

Although the role of the Wnt pathway in colon carcinogenesis has been described
previously, it has been recently demonstrated that Wnt signaling originates from highly …

Signal transduction enables cells to sense and respond to chemical and mechanical
information in the extracellular environment. Recently, phase separation has emerged as a …

Ribosome-associated protein quality control (RQC) is a protein surveillance mechanism that
eliminates defective nascent polypeptides. The E3 ubiquitin ligase, Ltn1, is a key regulator of …

We consider the Cahn–Hilliard equation with constant mobility and logarithmic potential on
a two-dimensional evolving closed surface embedded in, as well as a related weighted …

La vida nunca deja de sorprendernos. Hoy lo hace con unos orgánulos libres de membrana
conocidos como condensados biomoleculares. Éstos, son el resultado de un fenómeno de …