Roles of Porphyromonas gingivalis and its virulence factors in periodontitis
Periodontitis is an infection-driven inflammatory disease, which is characterized by gingival
inflammation and bone loss. Periodontitis is associated with various systemic diseases …
inflammation and bone loss. Periodontitis is associated with various systemic diseases …
Th17 cells in cancer: the ultimate identity crisis
T helper 17 (Th17) cells play a complex and controversial role in tumor immunity and have
been found to exhibit a fluctuating identity within the context of cancer. The recent …
been found to exhibit a fluctuating identity within the context of cancer. The recent …
Foxp3+ T cells expressing RORγt represent a stable regulatory T-cell effector lineage with enhanced suppressive capacity during intestinal inflammation
BH Yang, S Hagemann, P Mamareli, U Lauer… - Mucosal …, 2016 - nature.com
Foxp3 (forkhead box P3 transcription factor)-expressing regulatory T cells (Tregs) are
essential for immunological tolerance, best illustrated by uncontrolled effector T-cell …
essential for immunological tolerance, best illustrated by uncontrolled effector T-cell …
Peripheral CD4+ T‐cell differentiation regulated by networks of cytokines and transcription factors
J Zhu, WE Paul - Immunological reviews, 2010 - Wiley Online Library
CD4+ T cells, also known as T‐helper (Th) cells, play an important role in orchestrating
adaptive immune responses to various infectious agents. They are also involved in the …
adaptive immune responses to various infectious agents. They are also involved in the …
Transforming growth factor-β signaling in regulatory T cells controls T helper-17 cells and tissue-specific immune responses
Regulatory T cells (Treg cells) perform suppressive functions in disparate tissue
environments and against many inflammatory insults, yet the tissue-enriched factor (s) that …
environments and against many inflammatory insults, yet the tissue-enriched factor (s) that …
FOXP3+ Treg Cells and Gender Bias in Autoimmune Diseases
CD4+ CD25+ regulatory T (Treg) cells play a pivotal role in the maintenance of immune
homeostasis, where the X-linked master transcription factor forkhead box P3 (FOXP3) …
homeostasis, where the X-linked master transcription factor forkhead box P3 (FOXP3) …
Cutting edge: increased Il-17–secreting T cells in children with new-onset type 1 diabetes
AK Marwaha, SQ Crome… - The Journal of …, 2010 - journals.aai.org
Abstract CD4+ FOXP3+ regulatory T cells are essential for immune tolerance, and murine
studies suggest that their dysfunction can lead to type 1 diabetes (T1D). Human studies …
studies suggest that their dysfunction can lead to type 1 diabetes (T1D). Human studies …
Heterogeneity of T cells in atherosclerosis defined by single-cell RNA-sequencing and cytometry by time of flight
The infiltration and accumulation of pro-and anti-inflammatory leukocytes within the intimal
layer of the arterial wall is a hallmark of developing and progressing atherosclerosis. While …
layer of the arterial wall is a hallmark of developing and progressing atherosclerosis. While …
Generation of RORγt+ antigen-specific T regulatory 17 cells from Foxp3+ precursors in autoimmunity
Th17 cells are potent mediators in autoimmune diseases, and RORγt is required for their
development. Recent studies have shown that RORγt+ Treg cells in the gut regulate …
development. Recent studies have shown that RORγt+ Treg cells in the gut regulate …
Regulatory T-cell Response to Enterotoxigenic Bacteroides fragilis Colonization Triggers IL17-Dependent Colon Carcinogenesis
AL Geis, H Fan, X Wu, S Wu, DL Huso, JL Wolfe… - Cancer discovery, 2015 - AACR
Many epithelial cancers are associated with chronic inflammation. However, the features of
inflammation that are procarcinogenic are not fully understood. Regulatory T cells (Treg) …
inflammation that are procarcinogenic are not fully understood. Regulatory T cells (Treg) …