In this review, we aim to provide an overview of the recent advances in understanding
estrogen effects on the vascular endothelium. Epidemiological studies suggest the female …

The hypothalamic–pituitary–gonadal axis (HPG) plays vital roles in reproduction and steroid
hormone production in both sexes. The focus of this review is upon gene structures, receptor …

The endothelium plays a fundamental role in the biological processes that ensure
physiological vessel integrity, synthesizing numerous substances that are capable of …

Unlike age-matched men, premenopausal women benefit from cardiovascular protection.
Estrogens protect against apoptosis of endothelial cells (ECs), one of the hallmarks of …

Introduction Although clinical evidence supports an association between cardiovascular/
metabolic diseases (CVMD) and erectile dysfunction (ED), scientific evidence for this link is …

The ingestion of excess lipids often produces the accumulation of liver fat. The modulation of
diet energy partition affects this process and other metabolic responses, and oestrogens and …

Atherosclerotic cardiovascular disease is the leading cause of death worldwide. Intense
research in vascular biology has advanced our knowledge of molecular mechanisms of its …

In the current landscape of endothelial cell isolation for building in vitro models of the blood-
brain barrier, our work moves towards reproducing the features of the neurovascular unit to …

Дисфункция эндотелия является ранним маркером развития и прогрессии сердечно-
сосудистых заболеваний. Научные исследования последних лет доказали …

The vasomotor symptoms of menopause, including hot flashes, sweating, physical and
psychological discomfort, and emotional changes, are accurate and experienced by many of …