Adaptive deep brain stimulation: From experimental evidence toward practical implementation

WJ Neumann, R Gilron, S Little… - Movement …, 2023 - Wiley Online Library
Closed‐loop adaptive deep brain stimulation (aDBS) can deliver individualized therapy at
an unprecedented temporal precision for neurological disorders. This has the potential to …

Emerging technologies for improved deep brain stimulation

H Cagnan, T Denison, C McIntyre, P Brown - Nature biotechnology, 2019 - nature.com
Deep brain stimulation (DBS) is an effective treatment for common movement disorders and
has been used to modulate neural activity through delivery of electrical stimulation to key …

Long-term wireless streaming of neural recordings for circuit discovery and adaptive stimulation in individuals with Parkinson's disease

R Gilron, S Little, R Perrone, R Wilt… - Nature …, 2021 - nature.com
Neural recordings using invasive devices in humans can elucidate the circuits underlying
brain disorders, but have so far been limited to short recordings from externalized brain …

Deep brain stimulation in movement disorders: from experimental surgery to evidence‐based therapy

P Krack, J Volkmann, G Tinkhauser… - Movement …, 2019 - Wiley Online Library
Deep brain stimulation (DBS) of 3 different targets is the most important therapeutic
innovation of the past 30 years for patients with fluctuating Parkinson's disease (PD) …

Insights and opportunities for deep brain stimulation as a brain circuit intervention

WJ Neumann, A Horn, AA Kühn - Trends in Neurosciences, 2023 - cell.com
Deep brain stimulation (DBS) is an effective treatment and has provided unique insights into
the dynamic circuit architecture of brain disorders. This Review illustrates our current …

Biomarkers for closed-loop deep brain stimulation in Parkinson disease and beyond

W Bouthour, P Mégevand, J Donoghue… - Nature Reviews …, 2019 - nature.com
Subthalamic deep brain stimulation (DBS) for Parkinson disease (PD) currently requires
laborious open-loop programming, which can mitigate the benefits of this treatment …

Tourette syndrome: clinical features, pathophysiology, and treatment

KA Johnson, Y Worbe, KD Foote, CR Butson… - The Lancet …, 2023 - thelancet.com
Tourette syndrome is a chronic neurodevelopmental disorder characterised by motor and
phonic tics that can substantially diminish the quality of life of affected individuals. Evaluating …

Device profile of the percept PC deep brain stimulation system for the treatment of Parkinson's disease and related disorders

J Jimenez-Shahed - Expert Review of Medical Devices, 2021 - Taylor & Francis
Introduction: Several software and hardware advances in the field of deep brain stimulation
(DBS) have been realized in recent years and devices from three manufacturers are …

European clinical guidelines for Tourette syndrome and other tic disorders—version 2.0. Part IV: deep brain stimulation

N Szejko, Y Worbe, A Hartmann… - European Child & …, 2022 - Springer
Abstract In 2011 the European Society for the Study of Tourette Syndrome (ESSTS)
published its first European clinical guidelines for the treatment of Tourette Syndrome (TS) …

[HTML][HTML] Toward electrophysiology-based intelligent adaptive deep brain stimulation for movement disorders

WJ Neumann, RS Turner, B Blankertz, T Mitchell… - …, 2019 - Elsevier
Deep brain stimulation (DBS) represents one of the major clinical breakthroughs in the age
of translational neuroscience. In 1987, Benabid and colleagues demonstrated that high …