Fluid mechanics of heart valves and their replacements
As the pulsatile cardiac blood flow drives the heart valve leaflets to open and close, the flow
in the vicinity of the valve resembles a pulsed jet through a nonaxisymmetric orifice with a …
in the vicinity of the valve resembles a pulsed jet through a nonaxisymmetric orifice with a …
Calcific aortic stenosis—a review on acquired mechanisms of the disease and treatments
Calcific aortic stenosis is a progressive disease that has become more prevalent in recent
decades. Despite advances in research to uncover underlying biomechanisms, and …
decades. Despite advances in research to uncover underlying biomechanisms, and …
Dynamic and fluid–structure interaction simulations of bioprosthetic heart valves using parametric design with T-splines and Fung-type material models
This paper builds on a recently developed immersogeometric fluid–structure interaction
(FSI) methodology for bioprosthetic heart valve (BHV) modeling and simulation. It enhances …
(FSI) methodology for bioprosthetic heart valve (BHV) modeling and simulation. It enhances …
Lagrangian postprocessing of computational hemodynamics
SC Shadden, A Arzani - Annals of biomedical engineering, 2015 - Springer
Recent advances in imaging, modeling, and computing have rapidly expanded our
capabilities to model hemodynamics in the large vessels (heart, arteries, and veins). This …
capabilities to model hemodynamics in the large vessels (heart, arteries, and veins). This …
A novel mathematical model of activation and sensitization of platelets subjected to dynamic stress histories
Blood recirculating devices, such as ventricular assist devices and prosthetic heart valves,
are burdened by thromboembolic complications requiring complex and lifelong …
are burdened by thromboembolic complications requiring complex and lifelong …
Obstacles in haemocompatibility testing
W Van Oeveren - Scientifica, 2013 - Wiley Online Library
ISO 10993‐4 is an international standard describing the methods of testing of medical
devices for interactions with blood for regulatory purpose. The complexity of blood …
devices for interactions with blood for regulatory purpose. The complexity of blood …
Emerging trends in heart valve engineering: Part II. Novel and standard technologies for aortic valve replacement
The engineering of technologies for heart valve replacement (ie, heart valve engineering) is
an exciting and evolving field. Since the first valve replacement, technology has progressed …
an exciting and evolving field. Since the first valve replacement, technology has progressed …
Multiscale particle-based modeling of flowing platelets in blood plasma using dissipative particle dynamics and coarse grained molecular dynamics
We developed a multiscale particle-based model of platelets, to study the transport
dynamics of shear stresses between the surrounding fluid and the platelet membrane. This …
dynamics of shear stresses between the surrounding fluid and the platelet membrane. This …
Comparison of platelet activation through hinge vs bulk flow in bileaflet mechanical heart valves
M Hedayat, I Borazjani - Journal of biomechanics, 2019 - Elsevier
Bileaflet mechanical heart valves (BMHVs) are prone to thromboembolic complications
which are believed to be initiated by platelet activation. Platelets are activated by non …
which are believed to be initiated by platelet activation. Platelets are activated by non …
Mesoscale modeling: solving complex flows in biology and biotechnology
Fluids are involved in practically all physiological activities of living organisms. However,
biological and biorelated flows are hard to analyze due to the inherent combination of …
biological and biorelated flows are hard to analyze due to the inherent combination of …