Chondroitin sulfate (CS) is a member of glycosaminoglycans (GAGs) and has critical
physiological functions. CS is widely applied in medical and clinical fields. Currently, the …

Knee osteoarthritis (KOA) is the most common form of joint degeneration with increasing
prevalence and incidence in recent decades. KOA is a molecular disorder characterized by …

Sulfated glycosaminoglycans (GAGs) are a class of important biologics that are currently
manufactured by extraction from animal tissues. Although such methods are unsustainable …

Abstract Osteoarthritis (OA), as an “undead cancer”, causes a serious burden for both
individuals and society. In this study, a glycosaminoglycan-based injectable hydrogel was …

Chondroitin sulfate (ChS) is usually used as an oral nutraceutical supplement, and has been
popular in Asia, Europe, and United States for many years. In this study, a potential and …

This study designed to evaluate the effect of nutraceutical supplementation on pain intensity
and physical function in patients with knee/hip OA. The MEDLINE, Web of Science …

Osteoarthritis and type 2 diabetes mellitus are two prevalent chronic conditions that impose
a substantial burden on healthcare systems worldwide. The comorbidity of type 2 diabetes …

It has recently been demonstrated that chronic supplementation with nonanimal chondroitin
sulfate (nonanimal CS) in overweight subjects with knee osteoarthritis (OA) improves the …

With the gradual increase of the aging population in Chinese society, the incidence of knee
osteoarthritis showed an increasing trend. However, there are very few practical solutions for …

The short-term effect of glucosamine-sulfate, nonanimal chondroitin-sulfate, and S-adenosylmethionine
combination on ultrasonography findings, inflammation, pain, and functionality in patients with …