Background Diabetes has emerged as a major threat to health worldwide. Scope of Review
The exact mechanisms underlying the disease are unknown; however, there is growing …

Diabetes mellitus (DM) is a metabolic diseases characterized by hyperglycemia due to
insufficient or inefficient insulin secretory response. This chronic disease is a global problem …

Diabetes mellitus (DM) is a metabolic disorder caused by insufficient or inefficient insulin
secretary response and it is characterized by increased blood glucose levels …

This article provides an overview of approximately 300 secondary metabolites with inhibitory
activity against protein tyrosine phosphatase 1B (PTP1B), which were isolated from various …

(2 S, 3 R, 4 R, 5 S, 6 R)-2-(3-(4-Ethoxybenzyl)-4-chlorophenyl)-6-hydroxymethyl-tetrahydro-
2 H-pyran-3, 4, 5-triol (dapagliflozin; BMS-512148) is a potent sodium-glucose cotransporter …

Diabetes mellitus (DM), a chronic metabolic disease, severely affects patients' life and
intensively increases risks of developing other diseases. It is estimated that 0.4 billion …

Panax ginseng exhibits pleiotropic beneficial effects on cardiovascular system, central
nervous system, and immune system. In the last decade, numerous preclinical findings …

The incidence of insulin resistance has increased dramatically over the past several years,
and we and others have proposed that this increase may at least in part be attributable to …

Introduction: Protein tyrosine phosphatase 1B (PTP1B) inhibition has been recommended
as a crucial strategy to enhance insulin sensitivity in various cells and this fact is supported …

Protein tyrosine phosphatase 1B (PTP1B) is a crucial therapeutic target for multiple human
diseases comprising type 2 diabetes (T2DM) and obesity because it is a seminal part of a …