Endocrine disorders in Prader-Willi syndrome: a model to understand and treat hypothalamic dysfunction

M Tauber, C Hoybye - The Lancet Diabetes & Endocrinology, 2021 - thelancet.com
Prader-Willi syndrome is a rare genetic neurodevelopmental disorder resulting from the loss
of expression of maternally imprinted genes located in the paternal chromosomal region …

[HTML][HTML] Motor problems in Prader–Willi syndrome: A systematic review on body composition and neuromuscular functioning

L Reus, M Zwarts, LA van Vlimmeren… - Neuroscience & …, 2011 - Elsevier
Motor problems in Prader–Willi syndrome (PWS) are presumably related to abnormal body
composition and certain neuromuscular abnormalities. The authors reviewed the literature to …

Prader-Willi Syndrome

MG Butler - Neuroscience in the 21st Century: From Basic to …, 2022 - Springer
Since the first report of nine similarly affected individuals by Prader and colleagues in 1956,
a wealth of information has accumulated regarding the medical pathophysiology, genetic …

Prader-Willi syndrome: obesity due to genomic imprinting

M G. Butler - Current genomics, 2011 - benthamdirect.com
Prader-Willi syndrome (PWS) is a complex neurodevelopmental disorder due to errors in
genomic imprinting with loss of imprinted genes that are paternally expressed from the …

Importance of reward and prefrontal circuitry in hunger and satiety: Prader–Willi syndrome vs simple obesity

LM Holsen, CR Savage, LE Martin, AS Bruce… - International journal of …, 2012 - nature.com
Background: The majority of research on obesity (OB) has focused primarily on clinical
features (eating behavior, adiposity measures) or peripheral appetite-regulatory peptides …

Gait patterns in Prader-Willi and Down syndrome patients

V Cimolin, M Galli, G Grugni, L Vismara… - Journal of …, 2010 - Springer
Abstract Background Prader-Willi (PWS) and Down Syndrome (DS) are two genetic
disorders characterised by some common clinical and functional features. A quantitative …

Genetic conditions of short stature: A review of three classic examples

MG Butler, BS Miller, A Romano, J Ross… - Frontiers in …, 2022 - frontiersin.org
Noonan, Turner, and Prader-Willi syndromes are classical genetic disorders that are marked
by short stature. Each disorder has been recognized for several decades and is backed by …

Strength characterization of knee flexor and extensor muscles in Prader-Willi and obese patients

P Capodaglio, L Vismara, F Menegoni… - BMC musculoskeletal …, 2009 - Springer
Background despite evidence of an obesity-related disability, there is a lack of objective
muscle functional data in overweight subjects. Only few studies provide instrumental …

A guide to obesity and the metabolic syndrome

GA Bray - Florida: CRC, 2011 - api.taylorfrancis.com
If you have been to your local shopping mall recently and are older than 20 years of age,
you have witnessed the growing girth of many Americans. The United States is now the …

In adults with Prader–Willi syndrome, elevated ghrelin levels are more consistent with hyperphagia than high PYY and GLP-1 levels

L Purtell, L Sze, G Loughnan, E Smith, H Herzog… - Neuropeptides, 2011 - Elsevier
OBJECTIVE: Prader–Willi syndrome (PWS) is a leading genetic cause of obesity,
characterized by hyperphagia, endocrine and developmental disorders. It is suggested that …