Cerebral small vessel disease (SVD) causes lacunar stroke and intracerebral hemorrhage,
and is the most common pathology underlying vascular cognitive impairment. Increasingly …

Cerebral small vessel disease (CSVD) is the most common, chronic and progressive
vascular disease. The changes affect arterioles, capillaries and small veins supplying the …

Despite major technological advances in ischemic stroke diagnostic techniques, our current
understanding of stroke mechanisms and etiology continues to remain unclear in a …

Ischemic stroke classification is critical in conducting basic research and clinical practice. A
precise analysis of stroke subtypes requires the integration of clinical features, findings from …

Smith and Markus Cerebral Small Vessel Disease Trials 39 dysmetabolism, and glucose
dysregulation that are the primary targets for current ischemic stroke prevention. As an …

Background and Purpose—Posterior circulation stroke (PCS) account for 20% of all
ischemic strokes. There is limited evidence whether functional outcome of PCS is …

Ischemic stroke is a major cause of death and disability in adulthood worldwide. Because it
has highly heterogeneous phenotypes, phenotyping of ischemic stroke is an essential task …

Recent studies have uncovered that accumulation of glutamate after ischaemic stroke is
closely associated with the down-regulation of glutamate transporter-1 (GLT-1) expression …

Therapeutic effect of recombinant tissue-plasminogen activator (rt-PA) is time dependent.
There is limited evidence whether localization of stroke within the posterior circulation (PCS) …

5. Dwyer-Lindgren L, Bertozzi-Villa A, Stubbs RW, Morozoff C, Mackenbach JP, van Lenthe
FJ, et al. Inequalities in life expectancy among us counties, 1980 to 2014: temporal trends …